Early primary biliary cirrhosis: Just delayed or different?
K D Lindor – 30 December 2003
Liver injury associated with hepatitis C infection: Is it the virus or is it the host?
D L Thiele – 30 December 2003
Differential activation of heat shock and nuclear factor κB transcription factors in postischemic reperfused rat liver
L Tacchini, L Radice, G Pogliaghi, A Bernelli‐Zazzera – 30 December 2003 – The aim of this study was to investigate the behavior of the transcription factors, heat‐shock factor (HSF) and nuclear factor κB (NF‐κB), in postischemic reperfused liver, with particular attention paid to possible differences in the time‐course and mechanism of activation, which may help in defining their role in the response of the liver to reperfusion. Ischemia was induced by clamping the hilar pedicle of the left lateral and median liver lobes; the clamp was removed after 1 hour.
HBV precore mutants and response to interferon
M Lindh – 30 December 2003
Pitfall in the implication of intercellular adhesion molecule‐1 expression on isolated hepatocytes
S Mochida, A Ohno, K Fujiwara – 30 December 2003
Ammonia and GABA‐ergic neurotransmission: Interrelated factors in the pathogenesis of hepatic encephalopathy
A S Basile, E A Jones – 30 December 2003
A hepatitis B virus mutant with a new hepatocyte nuclear factor 1 binding site emerging in transplant‐transmitted fulminant hepatitis B
I Pult, T Chouard, S Wieland, R Klemenz, M Yaniv, H E Blum – 30 December 2003 – Hepatitis B virus (HBV) DNA was cloned from serum of a heart transplant recipient who died from fulminant hepatitis B transmitted by the donor. Restriction enzyme analyses of the clones obtained by conventional cloning yielded six HBV variants: a major species (pF‐1) representing 88% and five minor species (pF‐2 to pF‐6), each representing 2% to 4% of the clones.
Assessment of the role of activin A and transforming growth factor β in the regulation of AML12 cell growth
Y Zhang, H Mashima, M Kanzaki, H Shibata, I Kojima – 30 December 2003 – The present study was conducted to determine the role of two autocrine factors, activin A and transforming growth factor β (TGF‐β), in the growth regulation of AML12 hepatocytes. We overexpressed truncated type II activin and/or TGF‐β receptors in AML12 cells. In AML12 cells overexpressing truncated type II activin receptors (AML‐tAR cells), the inhibitory effect of activin A on DNA synthesis was completely blocked.
Hepatopulmonary syndrome versus portopulmonary hypertension: Distinctions and dilemmas
M J Krowka – 30 December 2003
Hepatitis G virus in patients with cryptogenic liver disease undergoing liver transplantation
M G Pessoa, N A Terrault, L D Ferrell, J P Kim, J Kolberg, J Detmer, M L Collins, A J Yun, M Viele, J R Lake, J P Roberts, N L Ascher, T L Wright – 30 December 2003 – To examine the prevalence of hepatitis G virus (HGV) in end‐stage liver disease of unknown cause and the role of HGV infection in posttransplantation hepatitis, we studied 46 patients undergoing liver transplantation (mean age, 50 years; M: F, 18:28) with cryptogenic cirrhosis. HGV RNA was detected by polymerase chain reaction (PCR) and was quantified by a branched DNA (bDNA) assay.