Analysis of direct‐acting antiviral‐resistant hepatitis C virus haplotype diversity by single‐molecule and long‐read sequencing

Kozue Yamauchi, Mitsuaki Sato, Leona Osawa, Shuya Matsuda, Yasuyuki Komiyama, Natsuko Nakakuki, Hitomi Takada, Ryo Katoh, Masaru Muraoka, Yuichiro Suzuki, Akihisa Tatsumi, Mika Miura, Shinichi Takano, Fumitake Amemiya, Mitsuharu Fukasawa, Yasuhiro Nakayama, Tatsuya Yamaguchi, Taisuke Inoue, Shinya Maekawa, Nobuyuki Enomoto – 30 March 2022 – The method of analyzing individual resistant hepatitis C virus (HCV) by a combination of haplotyping and resistance‐associated substitution (RAS) has not been fully elucidated because conventional sequencing has only yielded short and fragmented viral ge

LKB1 acts as a critical brake for the glucagon‐mediated fasting response

Suehelay Acevedo‐Acevedo, Megan L. Stefkovich, Sun Woo Sophie Kang, Rory P. Cunningham, Constance M. Cultraro, Natalie Porat‐Shliom – 30 March 2022 – As important as the fasting response is for survival, an inability to shut it down once nutrients become available can lead to exacerbated disease and severe wasting. The liver is central to transitions between feeding and fasting states, with glucagon being a key initiator of the hepatic fasting response. However, the precise mechanisms controlling fasting are not well defined.

A look into hemostatic characteristics during pediatric liver transplantation using the thromboelastometry (ROTEM®) test

Jun‐Ki Cho, Young‐Jin Moon, In‐Kyung Song, En‐Joo Kang, Won‐Jung Shin, Gyu‐Sam Hwang – 29 March 2022 – There is a paucity of evidence about the coagulation profile regarding the complexity of children undergoing liver transplantation (LT). This study aimed to investigate intraoperative hemostatic changes during pediatric LT according to the etiology for LT and examine the ability of rotational thromboelastometry (ROTEM®, TEM International GmbH, Munich, Germany) as a point‐of‐care monitoring method.

Reliability of extracellular contrast versus gadoxetic acid in assessing small liver lesions using liver imaging reporting and data system v.2018 and European association for the study of the liver criteria

Jordi Rimola, Víctor Sapena, Giuseppe Brancatelli, Anna Darnell, Laura Forzenigo, Aline Mähringer‐Kunz, Anita Paisant, Matteo Renzulli, Wolfgang Schima, Sylvain Terraz, Carlos Valls, Mathilde Wagner, Carmen Ayuso, Valerie Vilgrain, Maria Reig, Maxime Ronot – 28 March 2022

Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes

Sung Hwan Lee, Sun Young Yim, Yun Seong Jeong, Qi‐Xiang Li, Sang‐Hee Kang, Bo Hwa Sohn, Shwetha V. Kumar, Ji‐Hyun Shin, You Rhee Choi, Jae‐Jun Shim, Hayeon Kim, Ji Hoon Kim, Shin Kim, Sheng Guo, Randy L. Johnson, Ahmed Kaseb, Koo Jeong Kang, Yun Shin Chun, Hee Jin Jang, Byoung Gill Lee, Hyun Goo Woo, Min Jin Ha, Rehan Akbani, Lewis R. Roberts, David A. Wheeler, Ju‐Seog Lee – 28 March 2022

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