Masthead
14 March 2022
The fundamentals of sex‐based disparity in liver transplantation: Understanding can lead to change
Noreen Singh, Kymberly D. Watt, Rahima A. Bhanji – 14 March 2022 – Liver transplantation (LT) is the definitive treatment for end‐stage liver disease. Unfortunately, women are disadvantaged at every stage of the LT process. We conducted a literature review to increase the understanding of this disparity. Hormonal differences, psychological factors, and Model for End‐Stage Liver Disease (MELD) score inequalities are some pretransplantation factors that contribute to this disparity.
Mammalian Target of Rapamycin and Hepatocellular Carcinoma: The Question's Always There, Until We Choose To Answer It
Christopher J. Danford, Richard Gilroy – 14 March 2022
Transmembrane channel activity in human hepatocytes and cholangiocytes derived from induced pluripotent stem cells
Rodrigo M. Florentino, Qin Li, Michael C. Coard, Nils Haep, Takashi Motomura, Ricardo Diaz‐Aragon, Lanuza A. P. Faccioli, Sriram Amirneni, Zehra N. Kocas‐Kilicarslan, Alina Ostrowska, James E. Squires, Andrew P. Feranchak, Alejandro Soto‐Gutierrez – 14 March 2022 – The initial creation of human‐induced pluripotent stem cells (iPSCs) set the foundation for the future of regenerative medicine. Human iPSCs can be differentiated into a variety of cell types in order to study normal and pathological molecular mechanisms.
Hepatology Highlights
Jennifer L. Tomlinson, Joseph C. Ahn, Davide Povero, Resham Ramkissoon, Sumera I. Ilyas, Juan Pablo Arab – 14 March 2022
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14 March 2022
Many roads lead to Rome: The FGF4–AMP‐activated protein kinase–Caspase 6 signal axis in NAFLD and NASH
Alena Laschtowitz, Frank Tacke – 11 March 2022
Accurate long‐term prediction of death for patients with cirrhosis
David Goldberg, Alejandro Mantero, David Kaplan, Cindy Delgado, Binu John, Nadine Nuchovich, Ezekiel Emanuel, Peter P. Reese – 11 March 2022
Immunocompromised rabbit model of chronic HEV reveals liver fibrosis and distinct efficacy of different vaccination strategies
Qiyu He, Fan Zhang, Jingyi Shu, Shuangshuang Li, Zhaochao Liang, Minghao Du, Xing Liu, Tianxu Liu, Manyu Li, Xin Yin, Qiuwei Pan, Fengmin Lu, Ling Wang, Lin Wang – 11 March 2022
Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis
Lin Lei, Alix Bruneau, Haquima El Mourabit, Justine Guégan, Trine Folseraas, Sara Lemoinne, Tom Hemming Karlsen, Bénédicte Hoareau, Romain Morichon, Ester Gonzalez‐Sanchez, Claire Goumard, Vlad Ratziu, Pierre Charbord, Jérémie Gautheron, Frank Tacke, Thierry Jaffredo, Axelle Cadoret, Chantal Housset – 11 March 2022