Salvage liver transplantation or repeat hepatectomy for recurrent hepatocellular carcinoma: An intent‐to‐treat analysis

Chetana Lim, Hiroji Shinkawa, Kiyoshi Hasegawa, Prashant Bhangui, Chady Salloum, Concepcion Gomez Gavara, Eylon Lahat, Kiyohiko Omichi, Junichi Arita, Yoshihiro Sakamoto, Philippe Compagnon, Cyrille Feray, Norihiro Kokudo, Daniel Azoulay – 25 September 2017 – The salvage liver transplantation (LT) strategy was conceived for initially resectable and transplantable hepatocellular carcinoma (HCC) to obviate upfront transplantation, with salvage LT in the case of recurrence. The longterm outcomes of a second resection for recurrent HCC have improved.

Complexity and function of natural killer T cells with potential application to hepatic transplant survival

Randle Ware, Vipin Kumar – 25 September 2017 – One of the major innate‐like lymphocyte populations enriched in the liver consists of natural killer T (NKT) cells, which recognize self and foreign lipid antigens presented by the nonpolymorphic class I major histocompatibility complex–like molecule CD1d. NKT cells express natural killer cell markers as well as T cell receptors (TCRs) and can be classified into 2 categories: type I NKT cells use a semi‐invariant TCR, whereas type II NKT cells express diverse but still limited TCRs.

Hepatitis C virus testing for case identification in persons born during 1945‐1965: Results from three randomized controlled trials

Anthony K. Yartel, David B. Rein, Kimberly Ann Brown, Katherine Krauskopf, Omar I. Massoud, Cynthia Jordan, Natalie Kil, Alex D. Federman, David R. Nerenz, Joanne E. Brady, Danielle L. Kruger, Bryce D. Smith – 23 September 2017 – The Centers for Disease Control and Prevention and US Preventive Services Task Force recommend one‐time hepatitis C virus (HCV) testing for persons born during 1945‐1965 (birth cohort). However, few studies estimate the effect of birth cohort (BC) testing implementation on HCV diagnoses in primary care settings.

Nonalcoholic fatty liver disease incidence and impact on metabolic burden and death: A 20 year‐community study

Alina M. Allen, Terry M. Therneau, Joseph J. Larson, Alexandra Coward, Virend K. Somers, Patrick S. Kamath – 23 September 2017 – Recent population‐based data on nonalcoholic fatty liver disease (NAFLD) epidemiology in general, and incidence in particular, are lacking. We examined trends in NAFLD incidence in a U.S. community and the impact of NAFLD on incident metabolic comorbidities (MCs), cardiovascular (CV) events, and mortality.

Nonalcoholic fatty liver disease incidence and impact on metabolic burden and death: A 20 year‐community study

Alina M. Allen, Terry M. Therneau, Joseph J. Larson, Alexandra Coward, Virend K. Somers, Patrick S. Kamath – 23 September 2017 – Recent population‐based data on nonalcoholic fatty liver disease (NAFLD) epidemiology in general, and incidence in particular, are lacking. We examined trends in NAFLD incidence in a U.S. community and the impact of NAFLD on incident metabolic comorbidities (MCs), cardiovascular (CV) events, and mortality.

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