Ju Dong Yang, Ajitha Mannalithara, Andrew J. Piscitello, John B. Kisiel, Gregory J. Gores, Lewis R. Roberts, W. Ray Kim – 12 October 2017 – Surveillance for hepatocellular carcinoma (HCC) has been recommended in patients with cirrhosis. In this study, we examined the extent to which the competing risk of hepatic decompensation influences the benefit of HCC surveillance by investigating the impact of availability of liver transplantation (LTx) and the rate of progression of hepatic decompensation on survival gain from HCC surveillance.

Andrés Duarte‐Rojo, Astrid Ruiz‐Margáin, Aldo J. Montaño‐Loza, Ricardo U. Macías‐Rodríguez, Arny Ferrando, W. Ray Kim – 11 October 2017 – Sarcopenia and physical deconditioning are frequent complications in patients with cirrhosis and end‐stage liver disease (ESLD). They are the end result of impaired dietary intake, chronic inflammation, altered macronutrient and micronutrient metabolism, and low physical activity. Frailty is the end result of prolonged sarcopenia and physical deconditioning.

Sarah Shalaby, Alberto Zanetto, Alessandro Vitale, Martina Gambato, Umberto Cillo, Fabio Farinati, Patrizia Burra, Francesco Paolo Russo – 11 October 2017

James F. Trotter – 11 October 2017

Neil Mehta, Francis Y. Yao – 11 October 2017

Nicolás Goldaracena, Andre Gorgen, Gonzalo Sapisochin – 11 October 2017 – Cholangiocarcinoma (CCA) is the second most common liver cancer, and it is associated with a poor prognosis. CCA can be divided into intrahepatic, hilar, and distal. Despite the subtype, the median survival is 12‐24 months without treatment. Liver transplantation (LT) is recognized worldwide as a curative option for hepatocellular carcinoma. On the other hand, the initial results for LT for CCA were very poor mainly due to a lack of adequate patient selection.

Sangbin Han, Sanghoon Lee, Ju Dong Yang, Michael Douglas Leise, Joong Hyun Ahn, Seonwoo Kim, Kangha Jung, Mi Sook Gwak, Gaab Soo Kim, Justin Sangwook Ko – 11 October 2017 – Platelets interact with tumor cells and promote metastasis. The importance of platelets in posttransplant hepatocellular carcinoma (HCC) recurrence is unclear. Thus, we aimed to evaluate the association between preoperative platelet count (PLT) and HCC recurrence after living donor liver transplantation.

Nicolás Goldaracena, Andre Gorgen, Gonzalo Sapisochin – 11 October 2017 – Cholangiocarcinoma (CCA) is the second most common liver cancer, and it is associated with a poor prognosis. CCA can be divided into intrahepatic, hilar, and distal. Despite the subtype, the median survival is 12‐24 months without treatment. Liver transplantation (LT) is recognized worldwide as a curative option for hepatocellular carcinoma. On the other hand, the initial results for LT for CCA were very poor mainly due to a lack of adequate patient selection.

Stevan A. Gonzalez, James F. Trotter – 10 October 2017 – The use of hepatitis C virus (HCV)‐positive organs in liver transplantation (LT) has increased in the era of direct‐acting antiviral therapy. A rising demand for organs, the increased ability to effectively treat HCV infection in the transplant setting, and an unprecedented increase in HCV‐positive donors have all contributed to this trend. A recent abrupt rise in opioid use in the United States has resulted in a surge of injection drug use, transmission of HCV, and opioid‐related overdose deaths.

Adrian G. Murphy, Florin M. Selaru – 10 October 2017