Cynthia Lebeaupin, Déborah Vallée, Déborah Rousseau, Stéphanie Patouraux, Stéphanie Bonnafous, Gilbert Adam, Frederic Luciano, Carmelo Luci, Rodolphe Anty, Antonio Iannelli, Sandrine Marchetti, Guido Kroemer, Sandra Lacas‐Gervais, Albert Tran, Philippe Gual, Béatrice Bailly‐Maitre – 19 February 2018 – Endoplasmic reticulum (ER) stress is activated in nonalcoholic fatty liver disease (NAFLD), raising the possibility that ER stress‐dependent metabolic dysfunction, inflammation, and cell death underlie the transition from steatosis to steatohepatitis (nonalcoholic steatohepatitis; NASH).

Kyle Lewis, Takanori Takebe – 19 February 2018

Daniel Zamora‐Valdes, Kymberly D. Watt, Todd A. Kellogg, John J. Poterucha, Sara R. Di Cecco, Nicki M. Francisco‐Ziller, Timucin Taner, Charles B. Rosen, Julie K. Heimbach – 19 February 2018 – Obesity is increasingly common before and after liver transplantation (LT), yet optimal management remains unclear. The aim of this study was to analyze the long‐term outcomes for obese patients undergoing LT, including a noninvasive weight loss program and combined LT and sleeve gastrectomy (SG). Since 2006, all patients referred for LT with a body mass index (BMI) ≥35 kg/m2 were enrolled.

Ka Wing Ma, Kenneth Siu Ho Chok, Wong Hoi She, Albert Chi Yan Chan, Tan To Cheung, Wing Chiu Dai, James Yan Yue Fung, Chung Mau Lo – 16 February 2018 – Salvage liver transplantation (sLT) and repeated resection (RR) are effective treatments for recurrent hepatocellular carcinoma (HCC), and comparisons of the oncological outcomes between these 2 modalities were scarce. Consecutive patients admitted for either sLT or RR for recurrent HCC were recruited. All patients in the present series received either prior hepatectomy, ablative therapy, or both before RR or sLT.

Quirino Lai, Alessandro Vitale – 16 February 2018

Xiao‐Jing Zhang, Zhi‐Gang She, Hongliang Li – 16 February 2018

Peter T. W. Kim, Goran B. Klintmalm – 16 February 2018

Acute on chronic liver failure is increasingly understood in adults, less so in children. The aims of this Webinar are to increase understanding about the causes of acute liver decompensation in children with chronic, compensated liver disease, and the acute-care management of ACLF.John Bucuvalas (Moderator) John Bucuvalas MD, FAASLD is Professor of Pediatrics and has a broad background in transplant hepatology.

Young‐Chan Kwon, Keith Meyer, Guangyong Peng, Soumya Chatterjee, Daniel F. Hoft, Ranjit Ray – 14 February 2018 – A comprehensive strategy to control hepatitis C virus (HCV) infection needs a vaccine. Our phase I study with recombinant HCV E1/E2 envelope glycoprotein (EnvGPs) as a candidate vaccine did not induce a strong immune response in volunteers. We analyzed the interactions of HCV EnvGPs with human monocyte‐derived macrophages as antigen‐presenting cells.

Johnny Amer, Ahmad Salhab, Mazen Noureddin, Sarit Doron, Lina Abu‐Tair, Rami Ghantous, Mahmud Mahamid, Rifaat Safadi – 14 February 2018 – Insulin resistance is a key risk factor in the progression of nonalcoholic fatty liver disease (NAFLD) and may lead to liver fibrosis. Natural killer (NK) cells are thought to exert an antifibrotic effect through their killing of activated hepatic stellate cells (HSCs). Here, we investigated how the interplay between NK cells and HSCs are modified by insulin resistance in NAFLD.