Tumoroid à la carte: Path for personalization
Kyle Lewis, Takanori Takebe – 19 February 2018
Bax inhibitor‐1 protects from nonalcoholic steatohepatitis by limiting inositol‐requiring enzyme 1 alpha signaling in mice
Cynthia Lebeaupin, Déborah Vallée, Déborah Rousseau, Stéphanie Patouraux, Stéphanie Bonnafous, Gilbert Adam, Frederic Luciano, Carmelo Luci, Rodolphe Anty, Antonio Iannelli, Sandrine Marchetti, Guido Kroemer, Sandra Lacas‐Gervais, Albert Tran, Philippe Gual, Béatrice Bailly‐Maitre – 19 February 2018 – Endoplasmic reticulum (ER) stress is activated in nonalcoholic fatty liver disease (NAFLD), raising the possibility that ER stress‐dependent metabolic dysfunction, inflammation, and cell death underlie the transition from steatosis to steatohepatitis (nonalcoholic steatohepatitis; NASH).
DEP domain–containing mTOR–interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute‐on‐chronic liver injury in alcoholic liver disease
Hanqing Chen, Feng Shen, Alex Sherban, Allison Nocon, Yu Li, Hua Wang, Ming‐Jiang Xu, Xianliang Rui, Jinyan Han, Bingbing Jiang, Donghwan Lee, Na Li, Farnaz Keyhani‐Nejad, Jian‐gao Fan, Feng Liu, Amrita Kamat, Nicolas Musi, Leonard Guarente, Pal Pacher, Bin Gao, Mengwei Zang – 19 February 2018 – Alcoholic liver disease (ALD) is characterized by lipid accumulation and liver injury. However, how chronic alcohol consumption causes hepatic lipid accumulation remains elusive.
Higher retransplantation rate following extended right split‐liver transplantation: An analysis from the eurotransplant liver follow‐up registry
Roberta Angelico, Silvia Trapani, Michele Colledan, Umberto Cillo, Tullia Maria De Feo, Marco Spada – 19 February 2018
Assessment of the spectrum of hepatic encephalopathy: A multicenter study
Bradley Reuter, Kara Walter, Julien Bissonnette, Michael D. Leise, Jennifer Lai, Puneeta Tandon, Patrick S. Kamath, Scott W. Biggins, Christopher F. Rose, James B. Wade, Jasmohan S. Bajaj – 19 February 2018 – Hepatic encephalopathy (HE) is a major cause of morbidity in cirrhosis. However, its severity assessment is often subjective, which needs to be studied systematically. The aim was to determine how accurately trainee and nontrainee practitioners grade and manage HE patients throughout its severity.
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Peter T. W. Kim, Goran B. Klintmalm – 16 February 2018
Time to step‐up the fight against NAFLD
Xiao‐Jing Zhang, Zhi‐Gang She, Hongliang Li – 16 February 2018
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Quirino Lai, Alessandro Vitale – 16 February 2018
Defining Optimal Surgical Treatment for Recurrent Hepatocellular Carcinoma: A Propensity Score Matched Analysis
Ka Wing Ma, Kenneth Siu Ho Chok, Wong Hoi She, Albert Chi Yan Chan, Tan To Cheung, Wing Chiu Dai, James Yan Yue Fung, Chung Mau Lo – 16 February 2018 – Salvage liver transplantation (sLT) and repeated resection (RR) are effective treatments for recurrent hepatocellular carcinoma (HCC), and comparisons of the oncological outcomes between these 2 modalities were scarce. Consecutive patients admitted for either sLT or RR for recurrent HCC were recruited. All patients in the present series received either prior hepatectomy, ablative therapy, or both before RR or sLT.
LiverLearning®: 2018 Webinar: Acute on Chronic Liver Failure in Children
Acute on chronic liver failure is increasingly understood in adults, less so in children. The aims of this Webinar are to increase understanding about the causes of acute liver decompensation in children with chronic, compensated liver disease, and the acute-care management of ACLF.John Bucuvalas (Moderator) John Bucuvalas MD, FAASLD is Professor of Pediatrics and has a broad background in transplant hepatology.