Issue Information
23 February 2018
Elbasvir/grazoprevir and sofosbuvir for hepatitis C virus genotype 3 infection with compensated cirrhosis: A randomized trial
Graham R. Foster, Kosh Agarwal, Matthew E. Cramp, Sulleman Moreea, Stephen Barclay, Jane Collier, Ashley S. Brown, Stephen D. Ryder, Andrew Ustianowski, Daniel M. Forton, Ray Fox, Fiona Gordon, William M. Rosenberg, David J. Mutimer, Jiejun Du, Christopher L. Gilbert, Ernest Asante‐Appiah, Janice Wahl, Michael N. Robertson, Eliav Barr, Barbara Haber – 23 February 2018 – Many direct‐acting antiviral regimens have reduced activity in people with hepatitis C virus (HCV) genotype (GT) 3 infection and cirrhosis.
Issue Information
23 February 2018
Favorable response to mammalian target of rapamycin inhibition in a young patient with unresectable fibrolamellar carcinoma of the liver
Ruben Bill, Matteo Montani, Benedikt Blum, Jean‐François Dufour, Robert Escher, Michael Bühlmann – 23 February 2018
Updated Hepatitis B Guidance: Implications for liver transplant patients
Elizabeth C. Verna – 21 February 2018
Introducing Ronald J. Sokol, M.D.—our 2018 AASLD president
Cara L. Mack – 21 February 2018
The diminishing role of liver biopsy in living donor liver transplantation
James F. Trotter – 21 February 2018
New scoring classification for primary biliary cholangitis–autoimmune hepatitis overlap syndrome
Wei Zhang, Debapriya De, Kahee A. Mohammed, Satish Munigala, Guilan Chen, Jin‐Ping Lai, Bruce R. Bacon – 20 February 2018 – Autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) are two major immune‐mediated chronic liver diseases. Overlap syndrome (OS) is diagnosed if patients have features of both AIH and PBC; however, there is no consensus on the definition or diagnostic criteria for OS. Here, we report a new scoring classification for OS and evaluate its usefulness.
Uploading cellular batteries: Caring for mitochondria is key
Philipp Dutkowski, Pierre‐Alain Clavien – 20 February 2018
Assessment of the spectrum of hepatic encephalopathy: A multicenter study
Bradley Reuter, Kara Walter, Julien Bissonnette, Michael D. Leise, Jennifer Lai, Puneeta Tandon, Patrick S. Kamath, Scott W. Biggins, Christopher F. Rose, James B. Wade, Jasmohan S. Bajaj – 19 February 2018 – Hepatic encephalopathy (HE) is a major cause of morbidity in cirrhosis. However, its severity assessment is often subjective, which needs to be studied systematically. The aim was to determine how accurately trainee and nontrainee practitioners grade and manage HE patients throughout its severity.