Changes in natural killer cells and exhausted memory regulatory T Cells with corticosteroid therapy in acute autoimmune hepatitis

Hannah C. Jeffery, Manjit K. Braitch, Chris Bagnall, James Hodson, Louisa E. Jeffery, Rebecca E. Wawman, Lin Lee Wong, Jane Birtwistle, Helen Bartlett, Ansgar W. Lohse, Gideon M. Hirschfield, Jessica Dyson, David Jones, Stefan G. Hubscher, Paul Klenerman, David H. Adams, Ye H. Oo – 26 February 2018 – Autoimmune hepatitis (AIH) is an immune‐mediated liver disease currently treated by immunosuppressive medications with significant side effects. Thus, novel mechanistic treatments are greatly needed.

Nonalcoholic fatty liver disease contributes to subclinical atherosclerosis: A systematic review and meta‐analysis

Yao‐Yao Zhou, Xiao‐Dong Zhou, Sheng‐Jie Wu, Dan‐Hong Fan, Sven Poucke, Yong‐Ping Chen, Shen‐Wen Fu, Ming‐Hua Zheng – 26 February 2018 – Nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of atherosclerotic cardiovascular disease. In our meta‐analysis, we aimed to assess the correlation of NAFLD and four surrogate markers of subclinical atherosclerosis. PubMed, Embase, and the Cochrane Library were searched up until April 2017. Original studies investigating the association between NAFLD and subclinical atherosclerosis were included.

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