Radiotherapy for Hepatocellular Carcinoma Results in Comparable Survival to Radiofrequency Ablation: A Propensity Score Analysis

Koji Hara, Atsuya Takeda, Yuichiro Tsurugai, Yusuke Saigusa, Naoko Sanuki, Takahisa Eriguchi, Shin Maeda, Katsuaki Tanaka, Kazushi Numata – 25 February 2019 – Potentially curative treatments for early‐stage hepatocellular carcinoma (HCC) have drawbacks and contraindications. Recently, radiotherapy has achieved good outcomes. We compared the outcomes of radiotherapy and radiofrequency ablation (RFA) for early‐stage HCC. Consecutive patients with ≤3 early‐stage HCC lesions and tumor diameters ≤3 cm treated with RFA or radiotherapy were reviewed.

The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B

Laifeng Ren, Ming Zeng, Zizhi Tang, Mingyuan Li, Xiaojun Wang, Yang Xu, Yuding Weng, Xiaobo Wang, Huan Wang, Liandi Guo, Bing Zuo, Xin Wang, Si Wang, Jiangyan Lou, Yaxiong Tang, Dezhi Mu, Ning Zheng, Xianhui Wu, Junhong Han, Antony M. Carr, Penelope Jeggo, Cong Liu – 21 February 2019 – Chronic infection of hepatitis B virus (HBV) is associated with an increased incidence of hepatocellular carcinoma (HCC).

The Spectrum of Hepatic Involvement in Patients With Telomere Disease

Devika Kapuria, Gil Ben‐Yakov, Rebecca Ortolano, Min Ho Cho, Or Kalchiem‐Dekel, Varun Takyar, Shilpa Lingala, Naveen Gara, Michele Tana, Yun Ju Kim, David E. Kleiner, Neal S. Young, Danielle M. Townsley, Christopher Koh, Theo Heller – 21 February 2019 – Loss‐of‐function mutations in genes that encode for components of the telomere repair complex cause accelerated telomere shortening. Hepatic involvement has been recognized as a cause of morbidity in telomere diseases, but very few studies have characterized the nature and extent of liver involvement in affected patients.

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