Tanja Blumer, Isabel Fofana, Matthias S. Matter, Xueya Wang, Hesam Montazeri, Diego Calabrese, Mairene Coto‐Llerena, Tujana Boldanova, Sandro Nuciforo, Venkatesh Kancherla, Luigi Tornillo, Salvatore Piscuoglio, Stefan Wieland, Luigi M. Terracciano, Charlotte K.Y. Ng, Markus H. Heim – 6 May 2019 – Hepatocellular carcinoma (HCC) is the second leading cause of cancer‐related deaths worldwide. Treatment options for patients with advanced‐stage disease are limited. A major obstacle in drug development is the lack of an in vivo model that accurately reflects the broad spectrum of human HCC.

Yosuke Ashizawa, Satoshi Kuboki, Hiroyuki Nojima, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Shigetsugu Takano, Masaru Miyazaki, Masayuki Ohtsuka – 2 May 2019 – Olfactomedin 4 (OLFM4) induces signal transducer and activator of transcription 3 (STAT3) activation by inhibiting gene associated with retinoid‐interferon‐induced mortality 19 (GRIM19), a strong STAT3 suppressor gene; however, the mechanisms of OLFM4 for regulating GRIM19‐STAT3 cascade in hepatocellular carcinoma (HCC) remain unclear.

Sandeep Khurana, Harshit S. Khara – 2 May 2019

Koichiro Ohashi, Zhijun Wang, Yoon Mee Yang, Sandrine Billet, Wei Tu, Michael Pimienta, Suzanne L. Cassel, Stephen J. Pandol, Shelly C. Lu, Fayyaz S. Sutterwala, Neil Bhowmick, Ekihiro Seki – 1 May 2019 – Nonalcoholic fatty liver disease (NAFLD) enhances the growth and recurrence of colorectal cancer (CRC) liver metastasis. With the rising prevalence of NAFLD, a better understanding of the molecular mechanism underlying NAFLD‐associated liver metastasis is crucial. Tumor‐associated macrophages (TAMs) constitute a large portion of the tumor microenvironment that promotes tumor growth.

1 May 2019

Lydia Aye, Michael Volk – 1 May 2019

Raymond J. Lynch, Fei Ye, Quanhu Sheng, Zhiguo Zhao, Seth J. Karp – 30 April 2019

Daniel Berger, Vishal Desai, Sujit Janardhan – 30 April 2019

Tatyana Kushner, Rhoda S. Sperling, Douglas Dieterich – 30 April 2019

Bashar Attar – 30 April 2019