Andrew J. Muir, Cynthia Levy, Harry L.A. Janssen, Aldo J. Montano‐Loza, Mitchell L. Shiffman, Stephen Caldwell, Velimir Luketic, Dora Ding, Catherine Jia, Bryan J. McColgan, John G. McHutchison, G. Mani Subramanian, Robert P. Myers, Michael Manns, Roger Chapman, Nezam H. Afdhal, Zachary Goodman, Bertus Eksteen, Christopher L. Bowlus, for the GS‐US‐321‐0102 Investigators – 28 August 2018 – Lysyl oxidase like‐2 (LOXL2) plays a central role in fibrogenesis and is elevated in the serum and liver of patients with primary sclerosing cholangitis (PSC).

Li Yang, Ying Zhou, Pei‐pei Xu, Reena Mourya, Hai‐yan Lei, Guo‐qing Cao, Xiao‐li Xiong, Hui Xu, Xu‐fei Duan, Na Wang, Lin Fei, Xiao‐pan Chang, Xi Zhang, Meng Jiang, Jorge A. Bezerra, Shao‐tao Tang – 28 August 2018 – The diagnosis of biliary atresia (BA) remains a clinical challenge because affected infants have signs, symptoms, and serum liver biochemistry that are also seen in those with other causes of neonatal cholestasis (non‐BA). However, an early diagnosis and prompt surgical treatment are required to improve clinical outcome.

Ravi Sujan, Monica Cruz‐Lemini, Jose Altamirano, Douglas A. Simonetto, Rakhi Maiwall, Page Axley, Taylor Richardson, Vivek Desai, Joaquin Cabezas, Victor Vargas, Patrick S. Kamath, Vijay H. Shah, Shiv K. Sarin, Ramon Bataller, Ashwani K. Singal – 28 August 2018 – Identifying patients at high risk for acute kidney injury (AKI) during hospitalization among patients admitted with severe alcoholic hepatitis (AH) is an unmet clinical need. We performed a multicentric prospective cohort study using data from 4 different cohorts on well‐characterized patients hospitalized with severe AH.

Ann Robinson, Hesam Tavakoli, Benny Liu, Taft Bhuket, Robert J. Wong – 28 August 2018 – Individuals from the 1945‐1965 birth cohort account for the majority of hepatocellular carcinoma (HCC) cases in the United States. Understanding trends in HCC among this birth cohort is vital given the increasing burden of chronic liver disease among this group. We retrospectively evaluated trends and disparities in HCC tumor stage at the time of diagnosis among the 1945‐1965 birth cohort in the United States using the Surveillance, Epidemiology, and End Results (SEER) cancer registry.

A. Jasmine Bullard, Francesca E. Cunningham, Bryan D. Volpp, Elliott Lowy, Lauren A. Beste, Bernadette B. Heron, Mark Geraci, Julia M. Hammond, Kourtney LaPlant, Elise A. Stave, Marsha J. Turner, Meghan C. O’Leary, Michael J. Kelley, Christine M. Hunt – 28 August 2018 – Hepatitis B virus (HBV) reactivation may occur with high risk immunosuppression, such as anti‐cluster of differentiation (CD)20 antibodies (Abs). Appropriate HBV prophylaxis during anti‐CD20 Ab therapy averts hepatitis, chemotherapy disruption, and death.

Jonggi Choi, Gi‐Ae Kim, Seungbong Han, Woochang Lee, Sail Chun, Young‐Suk Lim – 28 August 2018 – We aimed to determine the surveillance performance of alpha‐fetoprotein (AFP), lectin‐reactive AFP (AFP‐L3), des‐gamma‐carboxy prothrombin (DCP), and their combinations for the early detection of hepatocellular carcinoma (HCC) by using prospectively collected longitudinal samples in patients at risk.

Lanna Little, Jody Rule, Lan Peng, Michelle Gottfried, William M. Lee, the Acute Liver Failure Study Group – 27 August 2018

Joana C. Branco, Ana Morbey, Américo Martins, Eduardo Barroso – 27 August 2018

Lanna Little, Jody Rule, Lan Peng, Michelle Gottfried, William M. Lee, the Acute Liver Failure Study Group – 27 August 2018

Ivan Linares, Nicolas Goldaracena, Roizar Rosales, Luis De la Maza, Moritz Kaths, Dagmar Kollmann, Juan Echeverri, Nazia Selzner, Stuart A. McCluskey, Gonzalo Sapisochin, Leslie B. Lilly, Paul Greig, Mamatha Bhat, Anand Ghanekar, Mark Cattral, Ian McGilvray, David Grant, Markus Selzner – 26 August 2018 – Portal vein thrombosis (PVT) is a severe complication after liver transplantation that can result in increased morbidity and mortality. Few data are available regarding risk factors, classification, and treatment of PVT after living donor liver transplantation (LDLT).