Making sense out of nonsense
Harold O. Conn – 1 July 1981
Muscle protein breakdown in liver cirrhosis and the role of altered carbohydrate metabolism
Giulio Marchesini, Marco Zoli, Angela Angiolini, Cristina Dondi, Francesco B. Bianchi, Emilio Pisi – 1 July 1981 – The rates of muscle protein breakdown, as estimated by the urinary excretion of 3‐methylhistidine, were assessed in 30 cirrhotics and 15 controls on a strictly controlled diet. 3‐Methylhistidine excretion was increased in cirrhotics irrespective of the etiology of the disease, and correlated with basal glucagon levels and with the insulin/glucagon ratio.
The mechanism of hepatic coma
Leslie Zieve – 1 July 1981
Notices
1 July 1981
δ antigen in hepatitis B: Immunohistology of frozen and paraffin‐embedded liver biopsies and relation to HBV infection
Elisabeth St. Öcklin, Fred Gudat, Gunthild Krey, Ursula Dürmüller, Markus Gasser, Martin Schmid, Georg Stalder, Leonardo Bianchi – 1 May 1981 – The finding that the recently described hepatitis B (HB)‐associated delta antigen (δ Ag) is preserved in pronase‐treated, formalin‐fixed paraffin sections allowed a combined prospective and retrospective immunohistological study of its occurrence in 571 liver biopsies.
Increase in ascites white blood cell and protein concentrations during diuresis in patients with chronic liver disease
John C. Hoefs – 1 May 1981 – Serum and ascites protein concentration and ascites cell concentration alterations were determined serially during diuresis in 27 patients with uncomplicated liver disease. The total protein concentration in ascites increased from 1.38 ± 0.96 gm% to 2.86 ± 1.28 gm% (p < 0.001); the serum protein concentration from 6.26 ± 0.81 gm% to 7.24 ± 0.93 gm% (p < 0.001), and the ascites to serum ratio of the total protein concentration from 0.21 ± 0.13 to 0.38 ± 0.14 (p < 0.001).
Notices
1 May 1981
A low molecular weight binding protein for organic anions (Z protein) from human hepatic cytosol: Purification and quantitation
Kazuaki Kamisaka, Hidenori Maezawa, Tooru Inagaki, Kenichi Okano – 1 May 1981 – Human Z protein from liver was purified to homogeneity. The protein has a molecular weight of 11,000 and an isoelectric point of pH 5.8. Circular dichroism spectra of Z protein‐bilirubin (uncon‐jugated and diglucuronide) complexes revealed two ellipticity extrema, a negative peak at 460 nm, and a positive peak at 410 nm. Human serum albumin had a higher affinity for bilirubin than did Z protein.