Louk H. P. M. Raedemakers, Maud I. Cleton, Carole Kooliman, Harold Baart de La Fajlle, Jan van Hattum – 1 March 1990 – Liver biopsy specimens obtained from two groups of erythrohepatic protoporphyria patients were studied histopathologically and ultrastructurally. Group 1 comprised seven erythrohepatic protoporphyria patients with a normal liver histology; from two patients liver biopsy specimens were available before and after 1 yr of chenodeoxycholic acid treatment.

Bruno Schneeweiss, Wolfgang Graninger, Peter Ferenci, Sabine Eichinger, Georg Grimm, Barbara Schneider, Anton N. Laggner, Kurt Lenz, Gunter Kleinberger – 1 March 1990 – Energy expenditure and substrate oxidation rate for fat, glucose and protein were evaluated by indirect calorimetry in 20 normal individuals, 35 patients with acute hepatitis and 22 patients with biopsyproven alcoholic cirrhosis in the postabsorptive state. Measurements were done in the resting state after an overnight fast (10 to 12 hr).

Jean D. Grange, Xavier Amiot, Veronique Grange, Laurent Gutmann, Michel Biour, François Bodin, Raoul Poupon – 1 March 1990 – Spontaneous bacterial peritonitis in cirrhosis is a serious complication that demands urgent attention. We report here a prospective study of the treatment of 27 episodes of spontaneous bacterial peritonitis in 22 cirrhotic patients with amoxicillin and clavulanic acid. The infection of ascitic fluid was diagnosed by a positive culture plus an ascitic neutrophil count exceeding 75/μl, or by an ascitic neutrophil count exceeding 500/μl.

Richard W. Light – 1 March 1990 – We reviewed the clinical data, hepatic histology, and microbiological features of 21 patients with previously documented acquired immune deficiency syndrome who had liver biopsies. Diagnoses of specific infections were made on liver biopsy in 11/21 patients (57%). Granulomas were found in 10/21 patients (48%) and were most often a manifestation of infection with Mycobacterium avium‐intracellulare.

Gary A. Clawson, Julie Sesno, Kathy Milam, Yan‐Fel Wang, Caroline Gabriel – 1 March 1990 – D‐galactosamine produces an early defect in protein synthesis, independent of its effects on RNA synthcsis. Here we show that the defect in protein synthesis is inherent in purified ribosomal subunits in vitro.

Barbara M. McFarlane, Jozsef Sipos, Christopher D. Gove, Ian G. McFarlane, Roger Williams – 1 March 1990 – Autoantibodies reacting with the galactose‐specific hepatic asialoglycoprotein receptor—a liver‐specific component expressed on the surfaces of hepatocytes—are often found in patients with chronic active hepatitis of presumed autoimmune origin.

Yasuhiro Takase, Susumu Shibuya, Fumio Chikamori, Kazuo Orii, Yoji Iwasaki – 1 March 1990 – High recurrence and rebleding rates have been reported when endocopic sclerotherapy has been performed on patients with esophageal varices. We studied the relationship between embolization range and recurrence rate in 26 patients in whom percutaneous transhepatic portography was carried out before and after sclerotherapy. Patients were divided into complete and incomplete embolization groups. The complete and incomplete embolization groups.

1 March 1990

Xavier Xiol, Jose Castellote, Carme Baliellas, Javier Ariza, Ana Gimenez Roca, Jordi Guardiola, Luis Casais – 1 March 1990 – Eleven episodes of spontaneous bacterial empyema were identified in eight cirrhotic patients with ascites. Criteria for spontaneous bacterial empyema included positive pleural fluid culture or polymorphonuclear cell concentration >500 cells/mm3, evidence of pleural effusion before an infectious episode and transudate characteristics during infection.

Donald J. Ritt – 1 March 1990