Steven Schenker, Henry S. Perkins, Michael F. Sorrell – 1 February 1990

S. K. Sarin – 1 February 1990 – Absolute alcohol is a potentially optimal agent for sclerotherapy of esophageal varices. It is cheap and readily available. We compared the efficacy and safety of alcohol with those of a commonly used sclerosing agent, polidocanol. The study was planned to include patients with previous bleeding from esophageal varices randomly assigned to one of the two treatments.

J. T. Beranek – 1 February 1990

Jean Pierre Vinel, Jean‐Luc Monnin, Jean‐Marc Combis, Paul Cales, Herve Desmorat, Jean‐Pierre Pascal – 1 February 1990 – Organic nitrates were reported to reduce portohepatic venous pressure gradient in patients with cirrhosis. However, these drugs lower arterial pressure and are well known to induce tolerace. The aim of the present study was to assess the hemodynamic effects of molsidomine, an antianginal agent, which does not induce tolerance and has little effect on arterial pressure in patients with normal liver, in 13 patients with alcoholic cirrhosis.

1 February 1990

Mercedes Roget, Maria Buti, Juan Ignacio Esteban, Rafael Esteban, Jaime Guardia, Albert J. Czaja, J. Eileen Hay, Jorge Rakela – 1 February 1990

Tien‐Chun Chang, Jyh‐Jian Lin, Shan‐Chang Yu, Tien‐Jye Chang – 1 January 1990 – Hepatocellular carcinoma is a hormone‐sensitive tumor. It has been reported that thyroxine and prolactin significantly stimulated hepatoma growth, whereas growth hormone failed to do so. To learn whether the growth hormone receptor is present in human hepatocellular carcinoma, we used radioreceptor assays in samples of human hepatocellular carcinoma. The liver tissues adjacent to hepatocellular carcinoma (mostly cirrhotic) and control liver tissues (taken during various surgical procedures) were also studied.

Swan N. Thung – 1 January 1990 – Nodular regenerative hyperplasia, a disorder characterized by regenerative nodules scattered diffusely throughout the liver without associated fibrosis, is most often recognized at autopsy when the entire liver is available for inspection. Diagnosis by needle biopsy is much more subtle.

Mordechai Rabinovitz, Judith S. Gavaler, Robert R. Schade, Vincents J. Dindzans, Mai‐Ching Chien, David H. Van Thiel – 1 January 1990 – Primary sclerosing cholangitis often occurs in association with inflammatory bowel disease, particularly ulcerative colitis but also Crohn's disease of the colon either with or without terminal ileal disease. Little data exist as to the effect of inflammatory bowel disease on the presenting symptoms, radiological features, response to liver transplantation, and potential risk of bile duct carcinoma in individuals with primary sclerosing cholangitis.

Nancy Rolando, Felicity Harvey, Javier Brahm, John Philpott‐Howard, Graeme Alexander, Alexander Gimson, Mark Casewell, Elizabeth Fagan, Roger Williams – 1 January 1990 – Fifty consecutive patients admitted with acute liver failure, minimal grade II encephalopathy, were studied prospectively to determine to incidence, timing and cause of bacterial infection, the relationship to clinical criterial for infection; and the influence of early microbiological diagnosis on clinical outcome.