Hajime Takikawa, Naoyo Sano, Tohru Narita, Yoshinobu Uchida, Masami Yamanaka, Tohru Horie, Takashi Mikami, Osamu Tagaya – 1 August 1991 – The hepatic transport of bile acid conjugates was studied in the Eisai hyperbilirubinuria rat, a Sprague‐Dawley mutant rat with conjugated hyperbilirubinemia. Serum bile acid levels were increased, bile acid‐independent bile flow was decreased and biliary glutathione concentrations were markedly decreased in the Eisai hyperbilirubinuria rat.

Itsuro Ogata, Satoshi Mochida, Tomoaki Tomiya, Kenji Fujiwara – 1 August 1991 – Hepatocyte contribution to hepatic collagen production in vivo was estimated in rats, based on the fact that ornithine is used for protein synthesis in the liver as arginine after conversion by way of the urea cycle only by hepatocytes. From rats given a mixture of [14C] ornithine and [3H]arginine, hepatic collagen and serum albumin were obtained. The hepatocyte contribution was calculated from the 14C and 3H in arginine purified from collagen and albumin by high performance liquid chromatography.

Mark P. Callery, Martin J. Mangino, M. Wayne Flye – 1 August 1991 – Prostaglandin‐E2 increases in liver tissue after partial hepatectomy and stimulates DNA synthesis in primary cultures of hepatocytes. This study evaluated the capacity of Kupffer cells isolated at various intervals after partial hepatectomy to produce prostaglandin E2 in response to bacterial endotoxin. This stimulator of Kupffer cells is a normal endogenous component of portal venous blood.

John Paul Roberts, Nancy L. Ascher, John Lake, Jan Capper, Sarla Purohit, Marvin Garovoy, Roy Lynch, Linda Ferrell, Teresa Wright – 1 August 1991 – Four cases of patients in whom graft vs. host disease developed after liver transplantation are described. The clinical course of each patient was similar with fever, pancytopenia, diarrhea and a skin rash developing 1 or 2 mo after liver transplantation. The clinical diagnosis was made from skin or colon biopsy specimens. Liver dysfunction did not occur in the patients at the time of diagnosis.

Han‐Chieh Lin, Olivier Soubrane, Didier Lebrec – 1 August 1991 – The hemodynamic effects, including mesentericsystemic shunts of early chronic administration of clonidine, were studied in conscious, unrestrained, portal vein‐stenosed rats.

Amadlo Telenti, Thomas F. Smith, Jurgen Ludwig, Michael R. Keating, Rund A. F. Krom, Russell H. Wiesner – 1 August 1991 – Epstein‐Barr virus infection has been associated with a broad spectrum of clinical manifestations, depending on the immune status of the host. In this report, we describe two liver transplant patients who received hepatic allografts from donors serologically positive for Epstein‐Barr virus and who experienced primary infection with Epstein‐Barr virus associated with prolonged liver graft dysfunction.

H. Thomas Schneider, Martin Fromm, Roland Ott, Paul Janowitz, Werner Swobodnik, Horst Neuhaus, Christian Ell – 1 August 1991 – To compare the fragmentation efficiency of three different shockwave systems, 63 human gallstone triplets were disintegrated in vitro using an electrohydraulic (MPL 9000, Dornier), an electromagnetic (Lithostar Plus, Siemens) and a piezoelectric (Piezolith 2300, R. Wolf) lithotripter. Since each stone triplet was obtained from the same gallbladder, the concrements of one such set were identical in physicochemical parameters.

Michael Houghton, Amy Weiner, Jang Han, George Kuo, Qui‐Lim Choo – 1 August 1991

Patrizia Pontisso, Alfredo Alberti, William P. J. Leenders, Sing‐Hiem Yap – 1 August 1991

Angelo Gatta, Paolo Angeli, Lorenza Caregaro, Francesca Menon, David Sacerdoti, Carlo Merkel – 1 August 1991 – It has been hypothesized that the magnitude of proximal sodium reabsorption affects the response to aldosterone antagonists in nonazotemic cirrhotic patients with ascites. To verify this hypothesis, we evaluated intrarenal sodium handling by lithium clearance in 51 nonazotemic ascitic cirrhotic patients and in 23 controls who were maintained on the same low‐sodium diet (80 mmol/day).