Judith K. Mickelson, Gilbert Kukielka, J. Stanley Bravenec, Elizabeth Mainolfi, Robert Rothlein, Hal K. Hawkins, James H. Kelly, C. Wayne Smith – 1 September 1995 – Intercellular adhesion molecule‐1 (ICAM‐1, CD54) is upregulated in many cell types stimulated by cytokines.
Alpha T. Banks, Hyman J. Zimmerman, Kamal G. Ishak, John G. Harter – 1 September 1995 – Diclofenac is a nonsteroidal anti–inflammatory drug approved in the United States in 1988 for the treatment of patients with osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis.
Wei Wang, Elliot Alpert – 1 September 1995 – We previously identified a specific receptor for alpha‐fetoprotein (AFP) on human monocytes. Although AFP alters many immune cell functions, the effect of AFP on monocyte cytokine production is unknown. Because tumor necrosis factor–alpha (TNF‐α) and interleukin‐1β (IL‐1β) are important cytokines in immunoregulation, we investigated whether AFP could modulate TNF‐α and IL‐1β production in U937, a human monocytic cell line.
Amnon Sonnenberg – 1 September 1995
Claudio Puoti, Andrea Magrini, Gloria Annovazzi, Alfonsa Pannullo, Teresa Filippi – 1 September 1995
François Mosimann, Solange Bresson‐Hadni, Georges Mantion, Michel Gillet, Rudolf W. Ammann – 1 September 1995
Nancy L. Ascher – 1 September 1995 – The shortage of organs for transplantation is especially severe for the critically ill newborn infant, for whom donors of the appropriate size are particularly scarce. One way to overcome this problem is to use animals in lieu of human as organ donors. The major limitation to using animals for this purpose is the susceptibility of animal organs to hyperacute rejection, a violent rejection reaction thought to be mediated by antidonor antibody and complement.
Jeffrey I. Frank – 1 September 1995
Michael Alt, Renate Renz, Peter H. Hofschneider, Gustav Paumgartner, Wolfgang H. Caselmann – 1 September 1995 – The inhibitory effect of antisense phosphorothioate oligodeoxynucleotides (S‐ODN) on hepatitis C viral gene expression was analyzed in an in vitro test system and in cell culture. S‐ODN were directed against different stem loop structures in the 5′noncoding region (NCR) of the hepatitis C virus (HCV) RNA and against a nucleotide stretch, including the start codon of the polyprotein precursor.