Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down‐regulation of cholesterol 7α‐hydroxylase and sterol 27‐hydroxylase gene transcription
Jaap Twisk, Marco F. M. Hoekman, Eline M. Lehmann, Piet Meijer, Willem H. Mager, Hans M. G. Princen – 1 February 1995 – Evidence from in vivo studies indicates that the bile acid pool and bile acid excretion are increased in humans with diabetes mellitus and in experimental diabetic animals, and that both parameters return to normal levels after administration of insulin.