Quantity and location of stone compounds, not the mere presence in small amounts within the stone fabric, are important factors for the correct classification of gallstones and a better knowledge of their pathogenesis

Prognosis of small hepatocellular carcinoma (less than 3 cm) after percutaneous acetic acid injection: Study of 91 cases

K Ohnishi, F Nomura, S Ito, K Fujiwara – 1 May 1996 – To assess the efficacy of ultrasound (US)‐guided percutaneous acetic acid (in concentrations of 15%, 20%, 30%, 40%, and 50%) injection for small hepatocellular carcinomas (HCCs) for long‐term prognosis, percutaneous acetic acid injection using 15% to 50% acetic acid was performed in 91 patients with one to four HCCs smaller than 3 cm during the past 6.5 years. During the series of treatment sessions for each patient, the same concentration of acetic acid was used.

Hepatitis C virus RNA in peripheral blood mononuclear cells: Comparing acute and chronic hepatitis C virus infection

T Chang, K Young, Y Yang, H Lei, H Wu – 1 May 1996 – Hepatitis C virus (HCV) can infect peripheral blood mononuclear cells (PBMC) of patients with chronic HCV infection. No data are available on PBMC testing for HCV RNA in acute hepatitis C. This study investigated the presence of HCV RNA in PBMC of patients with acute posttransfusion hepatitis C, compared with those with chronic HCV infection.

Role of Kupffer cells in arresting circulating tumor cells and controlling metastatic growth in the liver

L G Bayon, M A Izquierdo, I Sirovich, N van rooijen, R H Beelen, S Meijer – 1 May 1996 – Metastasis to the liver is a common event in clinical oncology. Blood‐borne tumor cells (TCs) arriving to the liver sinusoids run into a special vascular bed. The lining of liver sinusoids is shared by Kupffer cells (KCs) and endothelial cells. KCs, liver‐fixed macrophages, are responsible for detection and removal of “non‐self” particles.

Fibrous tumor‐liver interface in large hepatic neoplasms: Its significance for tumor resection and enucleation

Arthur Zimmermann, Hans‐Ulrich Baer – 1 May 1996 – Based on the clinical observation that large tumors located in the liver may be resected or enucleated with relative ease, the present retrospective study aimed at the detailed assessment of the tumor/liver interface in large hepatic neoplasms. For this purpose, a systematic light microscopic and immunohistochemical study on resection specimens of 10 giant hemangiomas, 10 hepatocellular carcinomas, and 9 liver metastases was performed.

Orthotopic liver transplantation for bone‐marrow transplant‐associated veno‐occlusive disease and graft‐versus‐host disease of the liver

Hugo R. Rosen, Paul Martin, Gary J. Schiller, Mary Territo, David N. Lewin, Christopher R. Shackleton, Ronald W. Busuttil – 1 May 1996 – Bone marrow transplantation (BMT) is a highly successful and curative therapy for many primary hematologic malignancies. However, hepatic dysfunction and failure are important causes of morbidity and mortality in this patient group after BMT. Hepatic failure can occur as a result of involvement by graft‐versus‐host disease (GVHD) or as a result of veno‐occlusive disease (VOD).

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