Massimo Bolognesi, Cristina Quaglio, Giancarlo Bombonato, Maria Guido, Luisa Cavalletto, Liliana Chemello, Carlo Merkel, Massimo Rugge, Angelo Gatta, David Sacerdoti – 6 March 2008 – Liver transplant recipients are a model of rapid progression of hepatitis C virus (HCV)–related liver disease, from normal to cirrhosis. The aim of the study was the analysis of the relationship between portohepatic hemodynamics and modification in liver histology during the progression of HCV liver disease after transplant. Patients transplanted for HCV cirrhosis were considered for the study.

Kirti Shetty, Munira Hussain, Lei Nei, K. Rajender Reddy, Anna S.F. Lok – 6 March 2008 – Occult hepatitis B virus (HBV) infection is defined as the detection of HBV deoxyribonucleic acid (DNA) in the serum or liver tissue of individuals who test negative for hepatitis B surface antigen (HBsAg). We undertook a prospective study to evaluate the significance and course of occult HBV in patients with hepatitis C virus (HCV) cirrhosis undergoing orthotopic liver transplantation (OLT).

Gin‐Ho Lo, Kwok‐Hung Lai – 6 March 2008

Tracy Swan, Raymond T. Chung – 5 March 2008

Resat Ozaras, Hakan Leblebicioglu, Cafer Eroglu – 5 March 2008

Jinlin Hou, Nathaniel Brown, JiDong Jia – 5 March 2008

Siew Chin Ong, Belinda Mak, Myat Oo Aung, Shu‐Chuen Li, Seng‐Gee Lim – 3 March 2008 – The relationship between stages of chronic hepatitis B liver disease and health‐related quality of life (HRQoL) is an important aspect of the overall management of hepatitis B virus (HBV) infection, yet is not well characterized. Consequently we sought to examine HRQoL in HBV patients, stratified by disease severity, compared with normal controls and hypertensive patients, using the Short Form 36 Health Survey (SF‐36) and the EQ‐5D self‐report questionnaire.

David T. Palma, George M. Philips, Miguel R. Arguedas, Susan M. Harding, Michael B. Fallon – 29 February 2008 – Sleep alters respiratory mechanics and gas exchange, which can adversely affect arterial oxygenation. Whether sleep affects oxygenation in hepatopulmonary syndrome is unknown. The aim of this study was to assess oxygen desaturation during sleep in hepatopulmonary syndrome. Twenty adults with cirrhosis including 10 controls and 10 patients with hepatopulmonary syndrome underwent home pulse‐oximetry during sleep.

Giovanni Musso, Roberto Gambino, Franco De Michieli, Marilena Durazzo, Gianfranco Pagano, Maurizio Cassader – 29 February 2008 – Factors underlying the independent association of nonalcoholic steatohepatitis (NASH) with increased cardiovascular risk are unknown. Adiponectin polymorphisms predict cardiometabolic risk in the general population. This association is not always mediated by low fasting adiponectin levels, adipose tissue accumulation, or traditional risk factors.

Federico Aucejo, Zuhaib Ibrahim, Koji Hashimoto, Cristiano Quintini, Dympna Kelly, David Vogt, Bijan Eghtesad, John Fung, Charles Miller, Ralph Tuthill – 27 February 2008 – Some chromosomal alterations can be associated with vascular abnormalities. For instance, Turner syndrome can be complicated by agenesis or hypoplasia of the portal venous system causing presinusoidal portal hypertension. Liver transplantation to treat this condition overcomes portal hypertension and reconstitutes the diminished hepatic function due to severe atrophy of the portal venous inflow.