Pierre‐Michel Huet, Lise Giroux, Marina Laurens, Dominique Crenesse – 26 March 2008 – Cirrhosis is known to induce capillarization of the sinusoidal endothelial cells (SECs) and collagenization of the space of Disse, resulting in a reduced access of plasma and plasma‐dissolved substances to hepatocytes due to their limited diffusion in the extravascular space. The aim of the present study was to use a well known effect of cold ischemia–warm reperfusion (CI‐WR) on liver SECs, that is, their retraction and detachment, progressing to a denudation of the SEC lining.

Jun Yu, Qian Tao, Kin F. Cheung, Hongchuan Jin, Fan Fong Poon, Xian Wang, Hongyu Li, Yuen Y. Cheng, Christoph Röcken, Matthias P. A. Ebert, Anthony T. C. Chan, Joseph J. Y. Sung – 26 March 2008 – The ubiquitin carboxyl‐terminal hydrolase L1 (UCHL1) is a carboxyl‐terminal ubiquitin hydrolase regulating cellular ubiquitin levels, recently suggested as a tumor suppressor. However, the role of UCHL1 in hepatocellular carcinoma (HCC) is not clear.

Marcela Castillo‐Rama, Maria Jose Castro, Ivan Bernardo, Juan Carlos Meneu‐Diaz, Almudena Moreno Elola‐Olaso, Sara M. Calleja‐Antolin, Eva Romo, Pablo Morales, Enrique Moreno, Estela Paz‐Artal – 26 March 2008 – The significance of human leukocyte antigen (HLA) compatibility and preformed antibodies in liver transplantation remains unclear. The objectives of this study were to evaluate, in a single‐center cohort comprising 896 liver transplants, whether the degree of donor‐recipient compatibility and preformed antibodies modified graft survival.

Sahar Hassan‐Khabbar, Charles‐Henry Cottart, Dominique Wendum, Françoise Vibert, Jean‐Pierre Clot, Jean‐François Savouret, Marc Conti, Valérie Nivet‐Antoine – 26 March 2008 – Liver ischemia‐reperfusion (I/R) injury occurs in many clinical conditions, including liver surgery and transplantation. Oxygen free radicals generated during I/R reduce endogenous antioxidant systems and contribute to hepatic injury. trans‐Resveratrol (trans‐3,5,4′‐trihydroxystilbene) is reported to have antioxidant properties. We investigated the effect of trans‐resveratrol on liver injury induced by I/R.

Michael Adler, Filip De Pauw, Pierre Vereerstraeten, Agnese Fancello, Jan Lerut, Peter Starkel, Hans Van Vlierberghe, Roberto Troisi, Vincent Donckier, Olivier Detry, Jean Delwaide, Peter Michielsen, Thierry Chapelle, Jacques Pirenne, Frederik Nevens – 26 March 2008 – Although hepatocellular carcinoma (HCC) has become a recognized indication for liver transplantation, the rules governing priority and access to the waiting list are not well defined.

Yaakov Nahmias, Martin L. Yarmush, Raymond T. Chung – 26 March 2008

Chun‐Tao Wai, Kang‐Hoe Lee, Kai‐Chah Tan – 26 March 2008

Vicky Lee Ng, Anthony R. Otley – 26 March 2008

Ayako Tsuchiya, Masahide Yazaki, Fuyuki Kametani, Yo‐ichi Takei, Shu‐ichi Ikeda – 26 March 2008 – To elucidate whether the amount of tissue‐deposited amyloid in familial amyloid polyneuropathy (FAP) patients decreases or increases over the long‐term course after liver transplantation (LT), we examined changes in histopathological and biochemical characteristics of abdominal fat amyloid in the transplanted patients with a postoperative history of more than 10 years.

Maria Elena Fortes, Cláudio Augusto Marroni, Pedro Luis Coser, Carlos Abaeté de los Santos – 26 March 2008 – The aim of the study was to disclose a possible association of hearing defects with the use of either cyclosporin (CyA) or tacrolimus (FK‐506) in patients undergoing liver transplantation (LT). Pure‐tone audiometry (PTA) was performed in the same 42 patients before and after LT. Audiometric frequencies recorded ranged from 250 to 8000 Hz. Patients were divided into 2 groups according to the use of CyA (n = 18) or FK‐506 (n = 24).