Chronic genotype 4 hepatitis C
Daniel F. Schafer – 7 April 2008
Sustained complete response and low complication rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis
Yun Ku Cho, Jae Kyun Kim – 7 April 2008
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Tito Livraghi – 7 April 2008
Cirrhosis and liver failure in nonalcoholic fatty liver disease: Molehill or mountain?
Michael Charlton – 5 April 2008
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Karen Madsen – 2 April 2008
Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo
Boris Görg, Natalia Qvartskhava, Verena Keitel, Hans J. Bidmon, Oliver Selbach, Freimut Schliess, Dieter Häussinger – 28 March 2008 – Oxidative stress plays a major role in cerebral ammonia toxicity and the pathogenesis of hepatic encephalopathy (HE). As shown in this study, ammonia induces a rapid RNA oxidation in cultured rat astrocytes, vital mouse brain slices, and rat brain in vivo.
Multidrug resistance–associated proteins are crucial for the viability of activated rat hepatic stellate cells
Rebekka A. Hannivoort, Sandra Dunning, Sara Vander Borght, Ben Schroyen, Jannes Woudenberg, Fiona Oakley, Manon Buist‐Homan, Fiona A. J. van den Heuvel, Mariska Geuken, Albert Geerts, Tania Roskams, Klaas Nico Faber, Han Moshage – 28 March 2008 – Hepatic stellate cells (HSCs) survive and proliferate in the chronically injured liver. ATP‐binding cassette (ABC) transporters play a crucial role in cell viability by transporting toxic metabolites or xenobiotics out of the cell.
Liver xenografts for the treatment of acute liver failure: Clinical and experimental experience and remaining immunologic barriers
Hidetaka Hara, Bruno Gridelli, Yih Jyh Lin, Amadeo Marcos, David K. C. Cooper – 26 March 2008 – A critical element restricting the application of liver transplantation is the shortage of human deceased donor organs. Xenotransplantation using pig organs might be a solution to this shortage.
Steroid‐free, tacrolimus‐basiliximab immunosuppression in pediatric liver transplantation: Clinical and pharmacoeconomic study in 50 children
Jérémie M. Gras, Sophie Gerkens, Claire Beguin, Magdalena Janssen, Françoise Smets, Jean‐Bernard Otte, Etienne Sokal, Raymond Reding – 26 March 2008 – Corticosteroid‐free immunosuppression (IS) may be potentially beneficial for transplanted patients, particularly children. The purpose of this study was to evaluate the efficacy and cost of such strategy in primary pediatric liver transplantation (LT). Fifty pediatric LT recipients were prospectively treated with a steroid‐free, tacrolimus‐basiliximab–based IS (group TB).