Tohru Itoh, Atsushi Miyajima – 1 October 2013 – The liver is renowned for its strong, robust regenerative capacity, employing different modes of regeneration according to type and extent of injury. The process of compensatory hypertrophy of the liver upon partial hepatectomy has been standing as a classical model for studying organ regeneration in mammals and a subject of exhaustive analyses. Meanwhile, in view of the physiological relevance for many of the human liver pathologies induced upon toxic insults or hepatitis, other injury models have recently drawn increasing attention.

Chi‐Kuan Chen, Ching‐Yao Yang, Kuo‐Tai Hua, Ming‐Chih Ho, Gunnar Johansson, Yung‐Ming Jeng, Chiung‐Nien Chen, Min‐Wei Chen, Wei‐Jiunn Lee, Jen‐Liang Su, Tsung‐Ching Lai, Chi‐Chi Chou, Bing‐Ching Ho, Chuan‐Fa Chang, Po‐Huang Lee, King‐Jen Chang, Michael Hsiao, Ming‐Tsan Lin, Min‐Liang Kuo – 1 October 2013 – Leukocyte cell‐derived chemotoxin 2 (LECT2) has been shown to act as a tumor suppressor in hepatocellular carcinoma (HCC). However, the underlying mechanism has not yet been completely defined.

Salvatore Sutti, Aastha Jindal, Irene Locatelli, Marco Vacchiano, Luca Gigliotti, Cristina Bozzola, Emanuele Albano – 1 October 2013 – Previous studies have shown that human nonalcoholic steatohepatitis (NASH) is often associated with the presence of circulating antibodies against protein adducted by lipid peroxidation products. Here we used the methionine‐choline deficient (MCD) model of NASH to characterize the possible involvement of adaptive immunity in NASH.

Ryan Law, Carlos Leal, Barham Abu Dayyeh, Michael D. Leise, Domingo Balderramo, Todd H. Baron, Andres Cardenas – 1 October 2013 – Endoscopic retrograde cholangiopancreatography (ERCP) is frequently used for diagnosis and therapeutic interventions in recipients of liver transplantation (LT) who develop biliary complications. Post–endoscopic retrograde cholangiopancreatography acute pancreatitis (PEP) is the most common major adverse event after ERCP; however, the frequency of PEP in LT recipients is not well established.

Masatoshi Kudo, Tadaaki Arizumi, Kazuomi Ueshima – 1 October 2013

Tetsuji Fujita – 1 October 2013

Ian A. Rowe, Richard Parker, Matthew J. Armstrong, Andrew L. King, Diarmaid D. Houlihan, David J. Mutimer – 1 October 2013

Antonio Sica, Pietro Invernizzi, Alberto Mantovani – 1 October 2013 – Resident and recruited macrophages are key players in the homeostatic function of the liver and in its response to tissue damage. In response to environmental signals, macrophages undergo polarized activation to M1 or M2 or M2‐like activation states. These are extremes of a spectrum in a universe of activation states. Progress has been made in understanding the molecular mechanisms underlying the polarized activation of mononuclear phagocytes.

Tohru Itoh, Atsushi Miyajima – 1 October 2013 – The liver is renowned for its strong, robust regenerative capacity, employing different modes of regeneration according to type and extent of injury. The process of compensatory hypertrophy of the liver upon partial hepatectomy has been standing as a classical model for studying organ regeneration in mammals and a subject of exhaustive analyses. Meanwhile, in view of the physiological relevance for many of the human liver pathologies induced upon toxic insults or hepatitis, other injury models have recently drawn increasing attention.

Wen‐Xing Ding – 1 October 2013