What are the outcomes of declining a public health service increased risk liver donor for patients on the liver transplant waiting list?

Kristopher P. Croome, David D. Lee, Surakit Pungpapong, Andrew P. Keaveny, C. Burcin Taner – 17 January 2018 – The tragedy of the national opioid epidemic has resulted in a significant increase in the number of opioid‐related deaths and accordingly an increase in the number of potential donors designated Public Health Service (PHS) increased risk. Previous studies have demonstrated reluctance to use these PHS organs, and as a result, higher discard rates for these organs have been observed.

Cellular Membrane Trafficking Machineries Used by the Hepatitis Viruses

Jun Inoue, Masashi Ninomiya, Tooru Shimosegawa, Mark A. McNiven – 13 January 2018 – While the life cycles of hepatitis viruses (A, B, C, D, and E) have been modestly characterized, recent intensive studies have provided new insights. Because these viruses “hijack” the membrane trafficking of the host cell machinery during replicative propagation, it is essential to determine and understand these specific cellular pathways. Hepatitis B virus (HBV) and hepatitis C virus are well known as leading causes of liver cirrhosis and hepatocellular carcinoma.

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