Jun Inoue, Masashi Ninomiya, Tooru Shimosegawa, Mark A. McNiven – 13 January 2018 – While the life cycles of hepatitis viruses (A, B, C, D, and E) have been modestly characterized, recent intensive studies have provided new insights. Because these viruses “hijack” the membrane trafficking of the host cell machinery during replicative propagation, it is essential to determine and understand these specific cellular pathways. Hepatitis B virus (HBV) and hepatitis C virus are well known as leading causes of liver cirrhosis and hepatocellular carcinoma.

Mingxuan Feng, Ping Wan, Bijun Qiu, Tao Zhou, Yi Luo, Lihong Gu, Jiachang Chi, Chengpeng Zhong, Yefeng Lu, Jianjun Zhang, Qiang Xia – 12 January 2018 – A stenotic or hypoplastic portal vein (PV) represents a challenge for PV reconstruction in pediatric living donor liver transplantation (LDLT). Several PV venoplastic techniques have been developed. However, we still seek improved venoplastic techniques with better efficacy and compatibility. From June 2016 to July 2017, 271 LDLT procedures were performed at the Department of Liver Surgery, Renji Hospital.

Samarth S. Patel, Eiman Nabi, Luis Guzman, Antonio Abbate, Chandra Bhati, Richard T. Stravitz, Trevor Reichman, Scott C. Matherly, Carolyn Driscoll, Hannah Lee, Velimir A. Luketic, Richard K. Sterling, Arun J. Sanyal, Vaishali Patel, Marlon Levy, Mohammad Shadab Siddiqui – 12 January 2018 – Coronary artery disease (CAD) is an important contributor to morbidity and mortality in patients undergoing liver transplantation (LT). However, the current literature is limited by sampling bias and nondefinitive assessment of CAD.

Shan‐Ying Wu, Sheng‐Hui Lan, Shang‐Rung Wu, Yen‐Chi Chiu, Xi‐Zhang Lin, Ih‐Jen Su, Ting‐Fen Tsai, Chia‐Jui Yen, Tsung‐Hsueh Lu, Fu‐Wen Liang, Chung‐Yi Li, Huey‐Jen Su, Chun‐Li Su, Hsiao‐Sheng Liu – 12 January 2018 – Dysfunction of degradation machineries causes cancers, including hepatocellular carcinoma (HCC). Overexpression of cyclin D1 in HCC has been reported. We previously reported that autophagy preferentially recruits and degrades the oncogenic microRNA (miR)‐224 to prevent HCC.

Kuan‐Yin Lin, Szu‐Min Hsieh, Hsin‐Yun Sun, Yi‐Chun Lo, Wang‐Huei Sheng, Yu‐Chung Chuang, Aristine Cheng, Sung‐Ching Pan, Guan‐Jhou Chen, Chien‐Ching Hung, Shan‐Chwen Chang – 12 January 2018 – Outbreaks of hepatitis A virus (HAV) infection have been occurring among men who have sex with men in the Asia‐Pacific region, the United States, and several European countries since June 2015 and recently among persons who are homeless and use illicit drugs in the United States.

Katrin Böttcher, Krista Rombouts, Francesca Saffioti, Davide Roccarina, Matteo Rosselli, Andrew Hall, TuVinh Luong, Emmanuel A. Tsochatzis, Douglas Thorburn, Massimo Pinzani – 12 January 2018 – Autoimmune liver diseases (AILDs) are chronic liver pathologies characterized by fibrosis and cirrhosis due to immune‐mediated liver damage.

Carolina Armengol, Stefano Cairo – 12 January 2018

Robert Holz, Andreas E. Kremer, Dieter Lütjohann, Hermann E. Wasmuth, Frank Lammert, Marcin Krawczyk – 10 January 2018 – Benign recurrent intrahepatic cholestasis (BRIC) is a peculiar familial disease caused by mutations of the genes encoding hepatocanalicular flippase for phosphatidylserine (ATP8B1; BRIC type 1) or the bile salt export pump (ABCB11; BRIC type 2). Here, we report on a patient with nasobiliary drainage‐refractory BRIC type 2 who improved under plasma separation and anion absorption therapy.

Yuli Cai, Honggui Li, Mengyang Liu, Ya Pei, Juan Zheng, Jing Zhou, Xianjun Luo, Wenya Huang, Linqiang Ma, Qiuhua Yang, Shaodong Guo, Xiaoqiu Xiao, Qifu Li, Tianshu Zeng, Fanyin Meng, Heather Francis, Shannon Glaser, Lulu Chen, Yuqing Huo, Gianfranco Alpini, Chaodong Wu – 9 January 2018 – Adenosine 2A receptor (A2AR) exerts protective roles in endotoxin‐ and/or ischemia‐induced tissue damage. However, the role for A2AR in nonalcoholic fatty liver disease (NAFLD) remains largely unknown.

Ruben Hernaez, Fasiha Kanwal, Hashem B. El‐Serag – 9 January 2018