Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease

Paola Dongiovanni, Marica Meroni, Rosellina M. Mancina, Guido Baselli, Raffaela Rametta, Serena Pelusi, Ville Männistö, Anna L. Fracanzani, Sara Badiali, Luca Miele, Stefania Grimaudo, Salvatore Petta, Elisabetta Bugianesi, Giorgio Soardo, Silvia Fargion, Jussi Pihlajamäki, Stefano Romeo, Luca Valenti – 25 April 2018 – Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver damage and has a strong genetic component.

Strategies That Reduce 90‐Day Readmissions and Inpatient Costs After Liver Transplantation

Joseph H. Zeidan, David M. Levi, Ruth Pierce, Mark W. Russo – 25 April 2018 – Liver transplantation (LT) is hospital‐resource intensive and associated with high rates of readmission. We have previously shown a reduction in 30‐day readmission rates by implementing a specifically designed protocol to increase access to outpatient care. The aim of this work is to determine if the strategies that reduce 30‐day readmission after LT were effective in also reducing 90‐day readmission rates and costs.

LiverLearning®: 2018 Webinar: Role of Diet and Exercise in the Management of NAFLD

In this webinar, we will review the role of diet and exercise in the management of NAFLD. Specifically, we will overview the data in support of specific nutritional programs and physical activity regimens that have been shown to improve histologic components of NAFLD and NASH. Lastly, we will outline the remaining knowledge gaps and barriers related to lifestyle interventions in the treatment of NAFLD/NASH.Michelle Long Michelle T.

Acute‐on‐Chronic Liver Failure: Getting Ready for Prime Time?

Jasmohan S. Bajaj, Richard Moreau, Patrick S Kamath, Hugo E. Vargas, Vicente Arroyo, K. Rajender Reddy, Gyongyi Szabo, Puneeta Tandon, Jody Olson, Constantine Karvellas, Thierry Gustot, Jennifer C. Lai, Florence Wong – 24 April 2018 – Acute on chronic liver failure (ACLF) is the culmination of chronic liver disease and extrahepatic organ failures, which is associated with a high short‐term mortality and immense health care expenditure. There are varying definitions for organ failures and ACLF in Europe, North America, and Asia.

External validation of the United Kingdom‐primary biliary cholangitis risk scores of patients with primary biliary cholangitis treated with ursodeoxycholic acid

Angela C. Cheung, Aliya F. Gulamhusein, Brian D. Juran, Erik M. Schlicht, Bryan M. McCauley, Mariza de Andrade, Elizabeth J. Atkinson, Konstantinos N. Lazaridis – 24 April 2018 – The United Kingdom‐Primary Biliary Cholangitis (UK‐PBC) risk scores are a set of prognostic models that estimate the risk of end‐stage liver disease in patients with PBC at 5‐, 10‐ and 15‐year intervals. They have not been externally validated outside the United Kingdom.

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