Taming the Savage Breast From Within: Transcription Factor 21, a Regulator of Stellate Cell Deactivation
Shuang Wang, Scott L. Friedman – 31 January 2020
New Insights Into Intestinal Failure–Associated Liver Disease in Children
Racha T. Khalaf, Ronald J. Sokol – 31 January 2020 – Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components of PN lipid emulsions, including plant sterols, interact with hepatic innate immune activation promoted by products of gut bacterial overgrowth/dysbiosis and altered intestinal barrier function (gut‐liver axis) and by episodes of sepsis to cause cholestasis and IFALD.
New Insights Into Intestinal Failure–Associated Liver Disease in Children
Racha T. Khalaf, Ronald J. Sokol – 31 January 2020 – Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components of PN lipid emulsions, including plant sterols, interact with hepatic innate immune activation promoted by products of gut bacterial overgrowth/dysbiosis and altered intestinal barrier function (gut‐liver axis) and by episodes of sepsis to cause cholestasis and IFALD.
Immune‐Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2–Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury
Zhongjie Yi, Meihong Deng, Melanie J. Scott, Guang Fu, Patricia A. Loughran, Zhao Lei, Shilai Li, Ping Sun, Chenxuan Yang, Wenbo Li, Hongbo Xu, Feizhou Huang, Timothy R. Billiar – 30 January 2020
Exercise‐Induced Hyperammonemia Does Not Precipitate Overt Hepatic Encephalopathy
Fei‐Pi Lin, Arny A. Ferrando, Richard A. Dennis, Michael A. Dunn, W. Ray Kim, Andrés Duarte‐Rojo – 30 January 2020
Improvement in Quality of Life and Decrease in Large‐Volume Paracentesis Requirements With the Automated Low‐Flow Ascites Pump
Florence Wong, Emily Bendel, Kenneth Sniderman, Todd Frederick, Ziv J. Haskal, Arun Sanyal, Sumeet K. Asrani, Jeroen Capel, Patrick S. Kamath – 30 January 2020 – The automated low‐flow ascites pump (alfapump) is an implantable device that drains ascites directly into the urinary bladder.
A Single‐Cell Perspective of the Mammalian Liver in Health and Disease
Xuelian Xiong, Henry Kuang, Tongyu Liu, Jiandie D. Lin – 30 January 2020
Exercise‐Induced Hyperammonemia Does Not Precipitate Overt Hepatic Encephalopathy
Fei‐Pi Lin, Arny A. Ferrando, Richard A. Dennis, Michael A. Dunn, W. Ray Kim, Andrés Duarte‐Rojo – 30 January 2020
Reply
Kazuki Takeishi, Toru Ikegami, Tomoharu Yoshizumi, Nao Fujimori, Masaki Mori – 30 January 2020
The Status of Liver Transplantation in the Middle East
Kamran B. Lankarani, Seyed Ali Malek Hosseini – 29 January 2020