Stathmin 1 Induces Murine Hepatocyte Proliferation and Increased Liver Mass

Enpeng Zhao, Yang Shen, Muhammad Amir, Alton B. Farris, Mark J. Czaja – 7 November 2019 – The endogenous cellular signals that initiate the transition of hepatocytes from quiescence to proliferation remain unclear. The protein stathmin 1 (STMN1) is highly expressed in dividing cells, including hepatocytes, and functions to promote cell mitosis through physical interactions with tubulin and microtubules that regulate mitotic spindle formation.

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