Mutations in the V‐ATPase Assembly Factor VMA21 Cause a Congenital Disorder of Glycosylation With Autophagic Liver Disease

Magda Cannata Serio, Laurie A. Graham, Angel Ashikov, Lars Elmann Larsen, Kimiyo Raymond, Sharita Timal, Gwenn Le Meur, Margret Ryan, Elzbieta Czarnowska, Jos C. Jansen, Miao He, Can Ficicioglu, Pavel Pichurin, Linda Hasadsri, Berge Minassian, Alessandra Rugierri, Hannu Kalimo, W. Alfredo Ríos‐Ocampo, Christian Gilissen, Richard Rodenburg, Johan W. Jonker, Adriaan G. Holleboom, Eva Morava, Joris A. Veltman, Piotr Socha, Tom H. Stevens, Matias Simons, Dirk J. Lefeber – 7 March 2020

Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease

Francisco J. Caballero‐Camino, Ivan Rivilla, Elisa Herraez, Oscar Briz, Alvaro Santos‐Laso, Laura Izquierdo‐Sanchez, Pui Y. Lee‐Law, Pedro M. Rodrigues, Patricia Munoz‐Garrido, Sujeong Jin, Estanislao Peixoto, Seth Richard, Sergio A. Gradilone, Maria J. Perugorria, Manel Esteller, Luis Bujanda, Jose J.G. Marin, Jesus M. Banales, Fernando P. Cossío – 7 March 2020

Direct‐Acting Antivirals and Hepatocellular Carcinoma: No Evidence of Higher Wait‐List Progression or Posttransplant Recurrence

Federico Piñero, Ilka Boin, Aline Chagas, Emilio Quiñonez, Sebastián Marciano, Mario Vilatobá, Luisa Santos, Margarita Anders, Sergio Hoyos Duque, Agnaldo Soares Lima, Josemaría Menendez, Martín Padilla, Jaime Poniachik, Rodrigo Zapata, Martín Maraschio, Ricardo Chong Menéndez, Linda Muñoz, Diego Arufe, Rodrigo Figueroa, Manuel Mendizabal, Sahara Hurtado Gomez, Raquel Stucchi, Claudia Maccali, Rodrigo Vergara Sandoval, Carla Bermudez, Lucas McCormack, Adriana Varón, Adrián Gadano, Juan Mattera, Fernando Rubinstein, Flair Carrilho, Marcelo Silva – 4 March 2020 – The association between direc

Hepatocellular Protein Arginine Methyltransferase 1 Suppresses Alcohol‐Induced Hepatocellular Carcinoma Formation by Inhibition of Inducible Nitric Oxide Synthase

Jie Zhao, Maura O'Neil, Michael Schonfeld, Amberly Komatz, Steven A. Weinman, Irina Tikhanovich – 4 March 2020 – Alcohol is a well‐established risk factor for hepatocellular carcinoma (HCC), but the mechanisms by which alcohol promotes liver cancer are not well understood. Studies suggest that ethanol may enhance tumor progression by increasing hepatocyte proliferation and through alcohol‐induced liver inflammation. Protein arginine methyltransferase 1 (PRMT1) is the main enzyme responsible for cellular arginine methylation.

Use of Hepatitis C Nucleic Acid Test–Positive Liver Allografts in Hepatitis C Virus Seronegative Recipients

Nadeem Anwar, Tiffany E. Kaiser, Khurram Bari, Michael Schoech, Tayyab S. Diwan, Madison C. Cuffy, Latifa Silski, Ralph C. Quillin, Kamran Safdar, Shimul A. Shah – 3 March 2020 – Because of underutilization of liver allografts, our center previously showed that hepatitis C virus (HCV) antibody–positive/nucleic acid test (NAT)–negative livers when transplanted into HCV nonviremic recipients were safe with a 10% risk of HCV transmission. Herein, we present our single‐center prospective experience of using HCV NAT+ liver allografts transplanted into HCV NAT– recipients.

Recommendations for Implementing Hepatitis C Virus Care in Homeless Shelters: The Stakeholder Perspective

J. Konadu Fokuo, Carmen L. Masson, August Anderson, Jesse Powell, Dylan Bush, Margaret Ricco, Barry Zevin, Claudia Ayala, Mandana Khalili – 3 March 2020 – Compared with the general population, homeless individuals are at higher risk of hepatitis C infection (HCV) and may face unique barriers in receipt of HCV care. This study sought the perspectives of key stakeholders toward establishing a universal HCV screening, testing, and treatment protocol for individuals accessing homeless shelters.

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