Silvia Sookoian, Carlos J. Pirola, Luca Valenti, Nicholas O. Davidson – 14 March 2020 – Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning worldwide epidemic whose etiology reflects multiple interactions between environmental and genetic factors. Here, we review the major pathways and dominant genetic modifiers known to be relevant players in human NAFLD and which may determine key components of the heritability of distinctive disease traits including steatosis and fibrosis.

Silvia Sookoian, Carlos J. Pirola, Luca Valenti, Nicholas O. Davidson – 14 March 2020 – Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning worldwide epidemic whose etiology reflects multiple interactions between environmental and genetic factors. Here, we review the major pathways and dominant genetic modifiers known to be relevant players in human NAFLD and which may determine key components of the heritability of distinctive disease traits including steatosis and fibrosis.

Monika Sarkar, Deirdre Sawinski, Lisa Coscia, the American Society of Transplantation, Women’s Health Community of Practice – 14 March 2020

Josh Levitsky, Elisa Gordon – 14 March 2020

Michael R. Lucey, Ashwani K. Singal – 14 March 2020

Chiao‐Ling Li, Ming‐Chih Ho, You‐Yu Lin, Sheng‐Tai Tzeng, Yun‐Ju Chen, Hsin‐Yung Pai, Ya‐Chun Wang, Chi‐Ling Chen, Yu‐Hsin Lee, Ding‐Shinn Chen, Shiou‐Hwei Yeh, Pei‐Jer Chen – 14 March 2020

Mussarat N. Rahim, Michael A. Heneghan – 13 March 2020

Manisha Verma, Elliot B. Tapper, Amit G. Singal, Victor Navarro – 13 March 2020 – Palliative care (PC) that has evolved from a focus on end‐of‐life care to an expanded form of holistic care at an early stage for patients with serious illnesses and their families is commonly referred to as nonhospice PC (or early PC). Patients with end‐stage liver disease (ESLD) suffer from a high symptom burden and a deteriorated quality of life (QOL), with uncertain prognosis and limited treatment options.

Anna Isaacs‐Ten, Marta Echeandia, Mar Moreno‐Gonzalez, Arlaine Brion, Andrew Goldson, Mark Philo, Angela M. Patterson, Aimee Parker, Mikel Galduroz, David Baker, Simon M. Rushbrook, Falk Hildebrand, Naiara Beraza – 13 March 2020

Thoetchai (Bee) Peeraphatdit, Jennifer Wang, Matthew A. Odenwald, Shaomin Hu, John Hart, Michael R. Charlton – 13 March 2020 – Immune checkpoint inhibitors (ICIs) are monoclonal antibodies targeting immune checkpoint molecules. ICIs are an immunotherapy for the treatment of many advanced malignancies. The advent of ICIs has been a major breakthrough in the field of oncology, a fact recognized by the 2018 Nobel Prize in Physiology or Medicine being awarded for the discovery.