Hepatology Highlights

Adam Buckholz, Robert S. Brown, Hirsh Trivedi, Muzammil M. Khan, Hira Hanif, Daryl T.Y. Lau, Amneet Hans, Giorgio Roccaro, Joseph F. Pisa, Nidhi Jalan‐Sakrikar, Robert E. Schwartz, Nicholas W. Russo, Tejasav S. Sehrawat, Enis Kostallari, Adebowale O. Bamidele, Gopanandan Parthasarathy – 23 December 2020

Efficacy and Safety of Cenicriviroc in Patients With Primary Sclerosing Cholangitis: PERSEUS Study

Bertus Eksteen, Christopher L. Bowlus, Aldo J. Montano‐Loza, Eric Lefebvre, Laurent Fischer, Pamela Vig, Eduardo Bruno Martins, Jawad Ahmad, Kidist K. Yimam, Paul J. Pockros, Jordan J. Feld, Gerald Minuk, Cynthia Levy – 22 December 2020 – Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease with no approved treatments. C‐C chemokine receptor types 2 and 5 (CCR2/CCR5) play an important role in inflammation and fibrosis and are potential therapeutic targets for PSC.

Portal Vein Complications After Adult Living Donor Liver Transplantation: Time of Onset and Deformity Patterns Affect Long‐Term Outcomes

Yuzuru Sambommatsu, Keita Shimata, Sho Ibuki, Yasuko Narita, Kaori Isono, Masaki Honda, Tomoaki Irie, Masashi Kadohisa, Seiichi Kawabata, Hidekazu Yamamoto, Yasuhiko Sugawara, Osamu Ikeda, Yukihiro Inomata, Taizo Hibi – 21 December 2020 – Portal vein complications (PVCs) after adult living donor liver transplantation (LDLT) are potentially lethal.

Effectiveness of a Decentralized Hub and Spoke Model for the Treatment of Hepatitis C Virus in a Federally Qualified Health Center

Sarah A. Rojas, Job G. Godino, Adam Northrup, Maureen Khasira, Aaron Tam, Lisa Asmus, Catherine Frenette, Christian B. Ramers – 21 December 2020 – Hepatitis C virus (HCV) is a major cause of cirrhosis, liver cancer, and mortality in the United States. We assessed the effectiveness of decentralized HCV treatment delivered by nurse practitioners (NPs), primary care physicians (PMDs), or an infectious disease physician (ID MD) using direct‐acting antivirals in a Federally Qualified Health Center (FQHC) in urban San Diego, CA.

Liver Stiffness by Transient Elastography to Detect Porto‐Sinusoidal Vascular Liver Disease With Portal Hypertension

Laure Elkrief, Marie Lazareth, Sylvie Chevret, Valérie Paradis, Marta Magaz, Lorraine Blaise, Laura Rubbia‐Brandt, Lucile Moga, François Durand, Audrey Payancé, Aurélie Plessier, Cendrine Chaffaut, Dominique Valla, Marion Malphettes, Alba Diaz, Jean‐Charles Nault, Pierre Nahon, Etienne Audureau, Vlad Ratziu, Laurent Castera, Juan‐Carlos Garcia Pagan, Nathalie Ganne‐Carrie, Pierre‐Emmanuel Rautou, the ANRS CO12 CirVir Group – 21 December 2020

A Real‐World Observational Cohort of Patients with Hepatocellular Carcinoma: Design and Rationale for TARGET‐HCC

Roniel Cabrera, Amit G. Singal, Massimo Colombo, R. Kate Kelley, Hannah Lee, Andrea R. Mospan, Tim Meyer, Pippa Newell, Neehar D. Parikh, Bruno Sangro, K. Rajender Reddy, Stephanie Watkins, Richard C. Zink, Adrian M. Di Bisceglie – 21 December 2020 – This study describes the design of the TARGET‐hepatocellular carcinoma (HCC) cohort and descriptive characteristics of the patient population at diagnosis among those who were enrolled in the cohort across academic and community clinical centers.

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