Gotaro Yamada, Ichinosuke Hyodo, Kazuo Tobe, Motowo Mizuno, Takashi Nishihara, Toshinari Kobayashi, Hideo Nagashima – 1 May 1986 – Subpopulations of lymphocytes in portal areas, especially infiltrating bile duct epithelia were analyzed by light and electron microscopy using indirect peroxidaselabeled antibody method and monoclonal antibodies against pan‐T (Leu 1), cytotoxic/suppressor T (Leu 2a), helper/inducer T (Leu 3a) and natural killer/K (Leu 7) and suppressor T (Leu 15) cells in liver biopsy specimens from four patients with primary biliary cirrhosis.

1 May 1986

Kathleen M. Nicholls, Michael D. Shapiro, Rudiger Kluge, Hsaio‐Min Chung, Daniel G. Bichet, Robert W. Schrier – 1 March 1986 – Sodium excretion in 13 patients with decompensated cirrhosis was measured under baseline conditions of water loading (n = 13) and during conditions designed to improve effective blood volume including: head‐out water immersion alone (n = 13); norepinephrine infusion alone (n = 6), and combined norepinephrine and head‐out water immersion (n = 6).

1 March 1986

William J. Lindblad, John T. Galambos – 1 March 1986

Lawrence Lumeng – 1 March 1986 – Markedly increased circulating concentrations of pyridoxal‐5′‐phosphate (PLP) were found in each of 14 patients representing all clinical forms of hypophosphatasia, an inborn error characterized by deficient activity of the tissue‐nonspecific (bone/liver/kidney) isoenzyme of alkaline phosphatase (AP). The mean PLP concentration in plasma was 1,174 nM (range, 214 to 3,839 nM) in the patients and 57 ± 26 nM (mean ± S.D.) in 38 control subjects.

Shou‐Dong Lee, Jaw‐Ching Wu, Jiin‐Yu Wang, Yang‐Te Tsai, Kwang‐Juei Lo, Benjamin N. Chiang – 1 March 1986

Alexander E. S. Gimson, John O'Grady, Roland J. Ede, Bernard Portmann, Roger Williams – 1 March 1986 – The clinical, laboratory and histological features of 47 patients with what is defined as late onset hepatic failure are reviewed. Twenty‐five of the patients werefemale and 22 male with a median age of 45 years. Hepatic dysfunction was severe as evidenced by the prolongation of prothrombin time (median = 32 sec, range = 17 to 120 sec).

B. Leggett, R. Collins, R. Prentice, L. W. Powell, Lawrence E. Gurian, Thomas M. Rogoff, Athol J. Ware, Burton Combes – 1 March 1986

Reginald G. Hanson, Marion G. Peters, Jay H. Hoofnagle – 1 March 1986 – B and T lymphocyte function was studied in 10 patients with chronic type B hepatitis before, during and after a 28‐day course of prednisolone therapy. Lymphocyte function was assessed by measuring the in vitro synthesis of immunoglobulin by peripheral blood mononuclear cells stimulated with pokeweed mitogen and by assaying lymphocyte proliferation in response to B and T cell mitogens.