James R. Baker – 1 August 1992 – Individuals with chronic hepatitis B virus (HBV) infection are generally divided into asymptomatic healthy carriers and patients with chronic liver disease. Several studies have suggested that the hepatitis B core antigen could be an immunological target of cytotoxic T lymphocytes (CTL). To investigate the possible pressure site from CTL, the entire core region of HBV DNA was sequenced in 30 subjects (10 asymptomatic healthy carriers and 20 patients with chronic liver disease).

1 August 1992

1 August 1992

Judith S. Gavaler, David H. van Thiel – 1 August 1992 – The derangements of levels of sex hormones and gonadotropins in alcoholic cirrhotic men are well delineated. The countersituation in alcoholic cirrhotic women has not yet been fully described. This study was performed in postmenopausal women among whom menstrual cycle variations in hormones no longer occur; with such a study population, it is possible to control for confounding factors and thus optimize detection of differences in levels of hormones and hormone interrelationships.

Tetsuji Kida, Yasuni Nakanuma, Tadashi Terada – 1 August 1992 – Cystic dilatation of peribiliary glands of intrahepatic and extrahepatic bile ducts was investigated in autopsied livers with adult polycystic disease (n = 8), in autopsied livers with solitary nonparasitic cysts (n = 18) and in normal autopsied livers (n = 23). In normal livers, cystic dilatation of intrahepatic peribiliary glands was absent or slight, when present. In livers with solitary nonparasitic cysts, cystic dilatation of intrahepatic peribiliary glands was present in varying degrees.

Anders Lindblad, Rolf Hultcrantz, Birgitta Strandvik – 1 August 1992 – To study the liver disease of patients with cystic fibrosis, percutaneous liver biopsies were performed in 10 patients with cystic fibrosis aged 6 to 22 yr.

Paulette Bioulac‐Sage, Liliane Dubuisson, Christiane Bedin, Pierre Gonzalez, Eliane de Tinguy‐Moreaud, Henri Garcin, Charles Balabaud – 1 August 1992 – Weaned male rats were fed a 4 ppm selenium diet. Compared after 2 mo with a control group fed a 0.4 ppm diet, the rats' body weights had not significantly decreased and liver function was normal, but portal pressure was 1.8 times higher (p < 0.05). Liver weight was slightly increased (10.3%; p < 0.05). All livers had an abnormal appearance.

1 August 1992

C. Minke Bakker, Herold J. Metselaar, Theo N. Groenland, Maria J. Gomes, Eduard A. R. Knot, Eric J. Hesselink, Solco W. Schalm, Jeanne Stibbe, Onno T. Terpstra – 1 August 1992 – The major cause of the increased tissue‐type plasminogen activator activity during orthotopic liver transplantation is still unclear. Both the lack of hepatic clearance of tissue‐type plasminogen activator in the anhepatic period and increased endothelial release from the graft on reperfusion have been proposed as the major causes.

Teresa L. Wright – 1 August 1992