Pierre Laurent‐Puig, Jean‐François Flejou, Monique Fabre, Pierre Bedossa, Jacques Belghiti, François Gayral, Dominique Franco – 1 November 1992 – Mutant p53 has been found in a wide variety of human malignancies including carcinomas of the lung, breast and colon.
Antonio Francavilla, Alessandro Azzarone, Guiseppe Carrieri, Carlo Scotti‐Fogueni, Qia‐Hua Zeng, Umberto Cillo, Kendrick Porter, Thomas E. Starzl – 1 November 1992 – Transforming growth factor‐β canceled the hepatocyte proliferation caused by transforming growth factor‐α when the two substances were mixed and administered through a disconnected central portal vein branch after creation of an Eck fistula.
Yoshihide Ishiki, Hiroo Ohnishi, Yasutoshi Muto, Kunio Matsumoto, Toshikazu Nakamura – 1 November 1992 – Hepatocyte growth factor, a potent mitogen for mature hepatocytes in vitro, seems to function as a hepatotrophic factor for liver regeneration. We examined the mitogenic effect of hepatocyte growth factor on mouse liver in vivo.
Henry C. Bodenheimer – 1 November 1992
Eugene R. Schiff – 1 November 1992
Russell H. Wiesner, Michael K. Porayko, E. Rolland Dickson, Gregory J. Gores, Nicholas F. Larusso, J. Eileen Hay, H. Erik Wahlstrom, Ruud A. F. Krom – 1 November 1992
Robert Cywes, Paul D. Greig, Glynn R. Morgan, Juan R. Sanabria, Pierre‐Alain Clavien, P. Robert C. Harvey, Steven M. Strasberg – 1 November 1992 – Organ donors are typically subject to acute hyponutrition that might affect postpreservation liver function. Livers from nutritionally supplemented rats function better after preservation than livers from fasted rats. We have developed a method to glycogenate the liver of large animals in the temporal context of a human donor liver operation and have studied the fate of glycogen stores during preservation.
Masaaki Masuhara, Sikandar L. Katyal, Toshikazu Nakamura, Hisashi Shinozuka – 1 November 1992 – Hepatocyte growth factor, a potent hepatocyte mitogen in vitro, appears to trigger hepatocyte regeneration after partial hepatectomy and after acute liver cell necrosis. Transforming growth factor‐α and transforming growth factor‐β may also be involved in the control of liver regeneration.
Minoru Nomoto, Yasurou Uchikosi, Natumi Kajikazawa, Yasuki Tanaka, Hitosi Asakura – 1 November 1992 – Among 1,098 liver biopsy specimens obtained from patients with various liver diseases characterized by liver injury, 58 epithelial cells whose cytoplasms stained positively by the periodic acid–Schiff stain (digested with diastase) were recognized in the interlobular bile ducts of 37 specimens from 36 patients.
Fred C. Fowler, Robert K. Banks, Mark E. Mailliard – 1 November 1992 – Liver regeneration occurs after removal of or damage to a portion of the liver; it leads to restoration of the original liver mass. The activities of three sodium‐dependent amino acid transporters‐system A, system N and system ASC‐were determined during a 5‐day period of liver regeneration in the rat. Seventy‐percent hepatectomy or laparotomy was performed in pairs of rats; these rats' livers were removed at different time points after surgery.