Renal effects of drugs used in the treatment of portal hypertension
Jens H. Henriksen, Helmer Ring‐Larsen – 1 September 1993
Liver transplantation, clinical teaching project. American Gastroenterological Association. Unit 7. By S.R. Vera, C.A. Riely, M.I. Burrell and R.S. Koff, Timonium, MD: Milner‐Fenwick Inc., 1993. $100.
Raymond S. Koff, Franklin M. Klion – 1 September 1993
Atlas of lapararoscopic surgery. Edited by E.J. Reddick, 116 pp. New York: Raven Press, 1992. $98.
Steven C. Simon – 1 September 1993
Prevention of spontaneous hepatocellular carcinoma in long‐evans cinnamon rats with hereditary hepatitis by th administration of d‐penicillamine
Kang Jong‐Hon, Yuji Togashi, Hiroshi Kasai, Masuo Hosokawa, Noritoshi Takeichi – 1 September 1993 – Acute hepatitis spontaneously develops in the Long‐Evans Cinnamon rat at the age of 4 mo, and eventually hepatocellular carcinoma develops after the chronic hepatitis that persists for over a year. Previously, abnormal copper accumulation was found in the livers of Long‐Evans Cinnamon rats from birth, and it was reported that short‐term administration of D‐penicillamine, a copper‐chelating agent, prevented acute hepatitis in Long‐Evans Cinnamon rats.
Fatty‐acid metabolism and the pathogenesis of hepatocellular carcinoma: Review and hypothesis
Robert K. Ockner, Raja M. Kaikaus, Nathan M. Bass – 1 September 1993 – Despite increasing understanding of the genetic control of cell growth and the identification of several involved chemical and infectious factors, the pathogenesis of clinical and experimental hepatocellular carcinoma remains unknown. Available evidence is consistent with the possibility that selected changes in the hepatocellular metabolism of long‐chain fatty acids may contribute significantly to this process.
Cryoglobulinemia and hepatatrophic viruses
Alfred L. Baker – 1 September 1993 – Essential mixed cryoglobulinemia is frequently associated with chronic hepatitis. This report presents four cases of cryoglobulinemia with vasculitis associated with chronic hepatitis related to hepatitis C virus infection. Hepatitis C virus infection was ascertained in the four patients by both the presence in the serum of anti‐HCV antibodies detected by the fourantigen recombinant immunoblot assay and of HCV RNA detected by polymerase chain reaction.
Masthead
1 September 1993
Visualization of the uptake and processing of oxidized low‐density lipoproteins in human and rat liver
Sebastiaan Esbach, Moniek N. Pieters, Johannes Van Der Boom, Donald Schouten, M. Niels Van Der Heyde, Paul J. M. Roholl, Adriaan Brouwer, Theo J. C. Van Berkel, Dick L. Knook – 1 September 1993 – The interaction of oxidized human low‐density lipoproteins with human and rat liver was analyzed by light and electron microscopy.
Effect of chronic iron overload on procollagen gene expression
Faye D. Roberts, Paul Charalambous, Linda Fletcher, Lawrie W. Powell, June W. Halliday – 1 September 1993 – The pathogenesis of hepatic fibrosis and cirrhosis in genetic hemochromatosis may involve a direct effect of excess iron on collagen synthesis in the liver. To investigate this theory, we measured procollagen messenger RNA levels (types I, III and IV) in the livers of rats in which we produced chronic parenchymal iron overload by feeding them dietary carbonyl iron (2.5%, wt/wt) for up to 18 mo.