28 June 2007

Thomas Soliman, Hubert Hetz, Christoph Burghuber, Georg Györi, Gerd Silberhumer, Rudolf Steininger, Ferdinand Mühlbacher, Gabriela A. Berlakovich – 28 June 2007 – The appropriate time point for starting immunosuppressive treatment with calcineurin inhibitors after orthotopic liver transplantation (OLT) has been a subject of debate. The aim of the study was to analyze the effects of anti‐thymocyte globulin (ATG) induction therapy on rejection, renal function, infection, tumor rate, and survival.

Sammy Saab, Mina K. Oh, Ayman B. Ibrahim, Francisco Durazo, Steven Han, Hasan Yersiz, Douglas G. Farmer, R. Mark Ghobrial, Leonard I. Goldstein, Myron J. Tong, Ronald W. Busuttil – 28 June 2007 – Adherence to antiviral therapy is essential to achieve sustained virological responses in patients treated for hepatitis C. An important limitation to use of appropriate doses of ribavirin is development of anemia. The aim of this study is to identify risk factors associated with anemia in liver transplant recipients undergoing treatment for recurrent hepatitis C virus (HCV).

Caroline Créput, Frederique Blandin, Benjamin Deroure, Bruno Roche, Faouzi Saliba, Bernard Charpentier, Didier Samuel, Antoine Durrbach – 28 June 2007 – Calcineurin inhibitors (CNIs) are the cornerstone of immunosuppression after liver transplantation. However, CNI treatment is frequently associated with chronic renal failure (CRF). The reduction or interruption of CNI may reduce renal failure.

Laura Cisneros, Maria‐Carlota Londoño, Carmen Blasco, Ramón Bataller, Rosa Miquel, Miquel Bruguera, Pere Ginès, Antoni Rimola – 28 June 2007 – The pathogenic mechanisms of accelerated graft fibrosis in hepatitis C recurrence after liver transplantation (LT) are not well established. The aim of the study was to assess whether a greater activation of hepatic stellate cells (HSC), the major collagen‐producing cells in the liver, can occur in these patients as compared to non‐LT patients with chronic hepatitis C.

George Imvrios, Vasilios Papanikolaou, Miltiadis Lalountas, Kaliopi Patsiaoura, Dimitrios Giakoustidis, Ioannis Fouzas, Eva Anagnostara, Nikolaos Antoniadis, Dimitrios Takoudas – 28 June 2007 – Approximately 60 cases of biliary papillomatosis have been reported in the world literature, while only 6 cases have been reported to be treated with liver transplantation.

Parisa Badiee, Parivash Kordbacheh, Abdolvahab Alborzi, SeyedAli Malekhoseini, Farideh Zeini, Hosein Mirhendi, Mahmood Mahmoodi – 28 June 2007 – Invasive fungal infections after liver transplantation (LT) have resulted in high mortality and potentially fatal complications. This study was undertaken to determine the accuracy of the panfungal polymerase chain reaction enzyme link immunosorbent assay (PCR‐ELISA) method in early diagnosis of invasive fungal infections in liver transplant recipients (LTRs).

Nevin Yilmaz, Mitchell L. Shiffman, R. Todd Stravitz, Richard K. Sterling, Velimir A. Luketic, Arun J. Sanyal, A. Scott Mills, Melissa J. Contos, Adrian Coterell, Daniel Maluf, Marc P. Posner, Robert A. Fisher – 28 June 2007 – Recurrence of hepatitis C virus (HCV) following liver transplantation (LT) is universal. A subset of these patients develop advanced fibrosis and cirrhosis and it is believed that this leads to increased posttransplantation mortality.

Mingqing Xu, Lunan Yan, Jichun Zhao, Bo Li, Tianfu Wen, Yong Zeng, Yukui Ma, Wentao Wang, Jaying Yang, Zheyu Chen – 28 June 2007

Albert M. Harary, Kareem Abu‐Elmagd, Ngoc Thai, Ron Shapiro, Satoru Todo, John J. Fung, Thomas E. Starzl – 28 June 2007 – In July 1988, the liver and pancreas of a cadaveric donor were transplanted separately into a man with type 1 diabetes with end‐stage chronic hepatitis B virus. Two features of the operation may help explain the patient's current status as the longest‐lived liver‐pancreas recipient. One was enteric drainage of pancreatic exocrine secretions. The other was delivery of the pancreas venous effluent to the host portal system and then directly to the hepatic allograft.