Telomere length is associated with intima‐media thickness in pediatric liver transplant patients: A prospective cohort study

Nima Memaran, Hannes Wilke, Rizky I. Sugianto, Ulrich Baumann, Elena Bauer, Maxine Swallow, Esther Beuke, Norman Junge, Eva D. Pfister, Carl Grabitz, Nicolas Richter, Imeke Goldschmidt, Bernhard M. W. Schmidt, Anette Melk – 5 June 2022 – Leukocyte telomere length (LTL) is a marker for biological age. Pediatric liver transplant recipients show a high rate of subclinical atherosclerosis, indicated by elevated intima‐media thickness (IMT). We hypothesized that atherosclerosis is associated with biological age in these patients and investigated the course of LTL over time.

Associations between six dietary habits and risk of hepatocellular carcinoma: A Mendelian randomization study

Yunyang Deng, Junjie Huang, Martin C. S. Wong – 5 June 2022 – Diet is reported to be associated with hepatocellular carcinoma (HCC), but whether there is a causal relationship remains unclear. This study aimed to explore the potential causal associations between dietary habits and HCC risk using Mendelian randomization in an East Asian population.

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper – 4 June 2022 – Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding, renal injury, falls, and hepatic encephalopathy.

Subscribe to