Elevated liver enzymes predict morbidity and mortality despite antiviral cure in patients with chronic hepatitis C: Data from the German Hepatitis C‐Registry

Frank Tacke, Hartwig Klinker, Klaus H. W. Boeker, Uta Merle, Ralph Link, Peter Buggisch, Dietrich Hüppe, Markus Cornberg, Christoph Sarrazin, Heiner Wedemeyer, Thomas Berg, Stefan Mauss, DHC‐R – 4 June 2022 – While direct‐acting antivirals (DAAs) cure chronic hepatitis C virus (HCV) infection in almost all patients, some patients remain at risk of liver disease despite HCV cure.

Burden of early hospitalization after simultaneous liver–kidney transplantation: Results from the US Multicenter SLKT Consortium

Pratima Sharma, Jiaheng Xie, Leyi Wang, Min Zhang, John Magee, Adeline Answine, Pranab Barman, Jennifer Jo, Jasmine Sinha, Aaron Schluger, Gabriel J. Perreault, Kara E. Walters, Giuseppe Cullaro, Randi Wong, Natalia Filipek, Scott W. Biggins, Jennifer C. Lai, Lisa B. VanWagner, Elizabeth C. Verna, Yuval A. Patel – 3 June 2022 – The burden of early hospitalization (within 6 months) following simultaneous liver–kidney transplant (SLKT) is not known. We examined risk factors associated with early hospitalization after SLKT and their impact on patient mortality conditional on 6‐month survival.

The role of transjugular intrahepatic portosystemic shunt in patients with cirrhosis and ascites: Recent evolution and open questions

Pierre Deltenre, Alberto Zanetto, Dario Saltini, Christophe Moreno, Filippo Schepis – 3 June 2022 – In selected patients with cirrhosis and ascites, transjugular intrahepatic portosystemic shunt (TIPS) placement improves control of ascites and may reduce mortality. In this review, we summarize the current knowledge concerning the use of TIPS for the treatment of ascites in patients with cirrhosis, from pathophysiology of ascites formation to hemodynamic consequences, patient selection, and technical issues of TIPS insertion.

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