Donor information for living donor liver transplantation: Where can comprehensive information be found?

Emmanuel Melloul, Dimitri Aristotle Raptis, Christian Eugen Oberkofler, Philipp Dutkowski, Mickael Lesurtel, Pierre‐Alain Clavien – 29 March 2012 – Recently published data show that a large number of candidates for living donor liver transplantation (LDLT) actively look for additional information on the Internet because today it represents the main source of information for many of them. However, little is known about the quality of the information on LDLT available on the Internet.

Recipient survival and graft survival are not diminished by simultaneous liver‐kidney transplantation: An analysis of the united network for organ sharing database

Eric F. Martin, Jonathan Huang, Qun Xiang, John P. Klein, Jasmohan Bajaj, Kia Saeian – 29 March 2012 – Recipients of solitary liver and kidney transplants are living longer, and this increases their risk of long‐term complications such as recurrent hepatitis C virus (HCV) and drug‐induced nephrotoxicity. These complications may require retransplantation. Since the adoption of the Model for End‐Stage Liver Disease, the number of simultaneous liver‐kidney transplantation (SLK) procedures has increased. However, there are no standardized criteria for organ allocation to SLK candidates.

Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes

Manal F. Abdelmalek, Mariana Lazo, Alena Horska, Susanne Bonekamp, Edward W. Lipkin, Ashok Balasubramanyam, John P. Bantle, Richard J. Johnson, Anna Mae Diehl, Jeanne M. Clark, and the Fatty Liver Subgroup of the Look AHEAD Research Group – 29 March 2012 – Fructose consumption predicts increased hepatic fibrosis in those with nonalcoholic fatty liver disease (NAFLD). Because of its ability to lower hepatic adenosine triphosphate (ATP) levels, habitual fructose consumption could result in more hepatic ATP depletion and impaired ATP recovery.

Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice

Yulia A. Nevzorova, Jörg‐Martin Bangen, Wei Hu, Ute Haas, Ralf Weiskirchen, Nikolaus Gassler, Sebastian Huss, Frank Tacke, Piotr Sicinski, Christian Trautwein, Christian Liedtke – 27 March 2012 – Liver fibrogenesis is associated with the transition of quiescent hepatocytes and hepatic stellate cells (HSCs) into the cell cycle. Exit from quiescence is controlled by E‐type cyclins (cyclin E1 [CcnE1] and cyclin E2 [CcnE2]). Thus, the aim of the current study was to investigate the contribution of E‐type cyclins for liver fibrosis in man and mice.

Subscribe to