Machine learning improves the accuracy of graft weight prediction in living donor liver transplantation

Mariano Cesare Giglio, Mario Zanfardino, Monica Franzese, Hazem Zakaria, Salah Alobthani, Ahmed Zidan, Islam Ismail Ayoub, Hany Abdelmeguid Shoreem, Boram Lee, Ho‐Seong Han, Andrea Della Penna, Silvio Nadalin, Roberto Ivan Troisi, Dieter Clemens Broering – 26 September 2022 – Precise graft weight (GW) estimation is essential for planning living donor liver transplantation to select grafts of adequate size for the recipient. This study aimed to investigate whether a machine‐learning model can improve the accuracy of GW estimation.

Sex‐specific analysis of microRNA profiles in HBV‐associated cirrhosis by small RNA‐sequencing

Kristy Kwan‐Shuen Chan, Kwan‐Yung Au, Wai‐Ching Fung, Cheuk‐Yan Wong, Albert Chi‐Yan Chan, Regina Cheuk‐Lam Lo – 26 September 2022 – Liver cirrhosis represents an advanced stage of chronic liver disease and is associated with significant morbidity, mortality, and risk of cancer development. While sex disparity of liver diseases has been observed, understanding at a genetic level awaits more thorough investigation.

Monitoring quality of care in hepatocellular carcinoma: A modified Delphi consensus

Ashika D. Maharaj, John Lubel, Eileen Lam, Paul J. Clark, Oliver Duncan, Jacob George, Gary P. Jeffrey, Lara Lipton, Howard Liu, Geoffrey McCaughan, Eu‐Ling Neo, Jennifer Philip, Simone I. Strasser, Katherine Stuart, Alexander Thompson, Jonathan Tibballs, Thomas Tu, Michael C. Wallace, Alan Wigg, Marnie Wood, Amany Zekry, Elysia Greenhill, Liane J. Ioannou, Golo Ahlenstiel, Kaye Bowers, Stephen J. Clarke, Anouk Dev, Michael Fink, Mark Goodwin, Christos S. Karapetis, Miriam T. Levy, Kate Muller, James O'Beirne, David Pryor, James Seow, Nicholas Shackel, Caroline Tallis, Nick Butler, John K.

Loss of phospholipase Cγ1 suppresses hepatocellular carcinogenesis through blockade of STAT3‐mediated cancer development

Eun‐Bi Seo, Hyun‐Jun Jang, Sun‐Ho Kwon, Yong‐Jin Kwon, Seul‐Ki Kim, Song‐Hee Lee, Ae Jin Jeong, Hyun Mu Shin, Yong‐Nyun Kim, Stephanie Ma, Haeryoung Kim, Yun‐Han Lee, Pann‐Ghill Suh, Sang‐Kyu Ye – 24 September 2022 – Phospholipase C gamma 1 (PLCγ1) plays an oncogenic role in several cancers, alongside its usual physiological roles. Despite studies aimed at identifying the effect of PLCγ1 on tumors, the pathogenic role of PLCγ1 in the tumorigenesis and development of hepatocellular carcinoma (HCC) remains unknown.

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