Approach to the patient with decompensated cirrhosis and aortic stenosis during liver transplantation evaluation

Nikki Duong, Veronica Nguyen, Lorenzo De Marchi, Arul Thomas – 26 September 2022 – Aortic stenosis (AS) is the most common valvular disease and is reported to be present in 2%–7% of people over the age of 65. Risk factors for aortic stenosis and NASH overlap; thus, as the population ages, there is an increased likelihood that patients undergoing liver transplantation evaluation may have severe aortic stenosis. There is a high mortality rate associated with cardiac surgeries in patients with cirrhosis.

Machine learning improves the accuracy of graft weight prediction in living donor liver transplantation

Mariano Cesare Giglio, Mario Zanfardino, Monica Franzese, Hazem Zakaria, Salah Alobthani, Ahmed Zidan, Islam Ismail Ayoub, Hany Abdelmeguid Shoreem, Boram Lee, Ho‐Seong Han, Andrea Della Penna, Silvio Nadalin, Roberto Ivan Troisi, Dieter Clemens Broering – 26 September 2022 – Precise graft weight (GW) estimation is essential for planning living donor liver transplantation to select grafts of adequate size for the recipient. This study aimed to investigate whether a machine‐learning model can improve the accuracy of GW estimation.

Sex‐specific analysis of microRNA profiles in HBV‐associated cirrhosis by small RNA‐sequencing

Kristy Kwan‐Shuen Chan, Kwan‐Yung Au, Wai‐Ching Fung, Cheuk‐Yan Wong, Albert Chi‐Yan Chan, Regina Cheuk‐Lam Lo – 26 September 2022 – Liver cirrhosis represents an advanced stage of chronic liver disease and is associated with significant morbidity, mortality, and risk of cancer development. While sex disparity of liver diseases has been observed, understanding at a genetic level awaits more thorough investigation.

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