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Katharine Secunda, Josh Levitsky – 30 January 2014
Liver transplantation for hepatocellular carcinoma with allografts from donors after circulatory death: Is the tumor recurrence genuinely increased?
Hynek Mergental, Firas Zahr Eldeen, Paolo Muiesan, Darius Mirza – 30 January 2014
No increase in blood transfusions during liver transplantation since the withdrawal of aprotinin
Nick Schofield, Anita Sugavanam, Karen Thompson, Susan V. Mallett – 30 January 2014 – The aims of this study were to determine whether the withdrawal of aprotinin (APRO) led to an increased bleeding risk in patients undergoing orthotopic liver transplantation (OLT). A retrospective analysis compared consecutive patients undergoing OLT and treated with aprotinin (APRO group; n = 100) with a group in which aprotinin was not used (no‐APRO group; n = 100). Propensity score matching was then performed for each group to identify 2 matched cohorts.
Pregnancy outcomes after living donor liver transplantation: Results from a Japanese survey
Shoji Kubo, Shinji Uemoto, Hiroyuki Furukawa, Koji Umeshita, Daisuke Tachibana, for the Japanese Liver Transplantation Society – 30 January 2014 – A national survey of pregnancy outcomes after living donor liver transplantation (LDLT) was performed in Japan. Thirty‐eight pregnancies in 30 recipients resulted in 31 live births (25 recipients), 3 artificial abortions in the first trimester (3 recipients), 1 spontaneous abortion (1 recipient), and 3 fetal deaths (3 recipients).
Operative outcomes of adult living donor liver transplantation and deceased donor liver transplantation: A systematic review and meta‐analysis
Ping Wan, Xin Yu, Qiang Xia – 30 January 2014 – Living donor liver transplantation (LDLT) has emerged as an alternative to deceased donor liver transplantation (DDLT) because of the increasing number of patients waiting for liver transplantation (LT). However, whether it can achieve operative outcomes similar to those achieved with DDLT for adult patients remains controversial. We conducted this meta‐analysis to compare the operative outcomes of LDLT and DDLT recipients.
Clinical implications of preoperative and intraoperative liver biopsies for evaluating donor steatosis in living related liver transplantation
Mi‐Jung Jun, Ju Hyun Shim, So Yeon Kim, Nieun Seo, Kang Mo Kim, Young‐Suk Lim, Han Chu Lee, Eunsil Yu, Sung‐Gyu Lee – 30 January 2014 – The role of liver biopsy in selecting optimal donors is an area of continuing controversy in living donor liver transplantation (LDLT). Our aim was to assess the potential implications of preoperative and intraoperative biopsies for evaluating donor liver fat content.
Hepatology highlights
Jean‐François Dufour – 29 January 2014
Hepatology highlights
Jean‐François Dufour – 29 January 2014
Antibody‐mediated rejection in liver transplantation: Current controversies and future directions
Timucin Taner, Mark D. Stegall, Julie K. Heimbach – 27 January 2014 – Interest in the role of donor‐specific human leukocyte antibodies in liver transplantation has been rekindled recently. Emerging evidence suggests that these antibodies may cause injury to the liver allograft. Here we review the clinical literature, highlight controversial results, and propose a path forward for the definition and better understanding of antibody‐mediated injury to the liver. Liver Transpl 20:514–527, 2014. © 2014 AASLD.
Functional genomics identified a novel protein tyrosine phosphatase receptor type f‐mediated growth inhibition in hepatocarcinogenesis
Rabindranath Bera, Chih‐Yung Chiou, Ming‐Chin Yu, Jei‐Ming Peng, Chung‐Ru He, Chih‐Yun Hsu, Hsiao‐Ling Huang, Uda Y. Ho, Shi‐Ming Lin, Yu‐Jr Lin, Sen‐Yung Hsieh – 27 January 2014 – It is unclear how proliferating cells elicit suppression on cell proliferation and how cancer cells evade this growth suppression.