Issue Information
7 July 2017
Is antibody to surface antigen associated with hepatitis B reactivation in patients with resolved hepatitis B?
Yi‐Hsiang Huang, Shou‐Dong Lee – 7 July 2017
Reply
Sonali Paul – 7 July 2017
Determination of hepatocellular carcinoma grade by needle biopsy is unreliable for liver transplant candidate selection
Colin M. Court, Michael P. Harlander‐Locke, Daniela Markovic, Samuel W. French, Bita V. Naini, David S. Lu, Steven S. Raman, Fady M. Kaldas, Ali Zarrinpar, Douglas G. Farmer, Richard S. Finn, Saeed Sadeghi, James S. Tomlinson, Ronald W. Busuttil, Vatche G. Agopian – 7 July 2017 – The objective of this article is to evaluate the utility of preoperative needle biopsy (PNB) grading of hepatocellular carcinoma (HCC) as a biomarker for liver transplantation (LT) candidate selection.
Reply
Angels Escorsell, Jaime Bosch – 6 July 2017
Is the regulatory effect of PCAF and sirtuin 7 on phosphoglycerate kinase 1 acetylation a universal mechanism underlying hepatocellular carcinoma progression?
Changwei Dou, Xin Zheng, Qingguang Liu, Kangsheng Tu – 6 July 2017
Hospital volume and mortality after transjugular intrahepatic portosystemic shunt creation in the United States
Ammar Sarwar, Lujia Zhou, Victor Novack, Elliot B. Tapper, Michael Curry, Raza Malik, Muneeb Ahmed – 6 July 2017 – The link between higher procedure volume and better outcomes for surgical procedures is well established. We aimed to determine whether procedure volume affected inpatient mortality in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS). An epidemiological analysis of an all‐payer database recording hospitalizations during 2013 in the United States (Nationwide Readmissions Database) was performed.
Hospital volume and mortality after transjugular intrahepatic portosystemic shunt creation in the United States
Ammar Sarwar, Lujia Zhou, Victor Novack, Elliot B. Tapper, Michael Curry, Raza Malik, Muneeb Ahmed – 6 July 2017 – The link between higher procedure volume and better outcomes for surgical procedures is well established. We aimed to determine whether procedure volume affected inpatient mortality in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS). An epidemiological analysis of an all‐payer database recording hospitalizations during 2013 in the United States (Nationwide Readmissions Database) was performed.
A single‐cell transcriptomic analysis reveals precise pathways and regulatory mechanisms underlying hepatoblast differentiation
Li Yang, Wei‐Hua Wang, Wei‐Lin Qiu, Zhen Guo, Erfei Bi, Cheng‐Ran Xu – 6 July 2017 – How bipotential hepatoblasts differentiate into hepatocytes and cholangiocytes remains unclear. Here, using single‐cell transcriptomic analysis of hepatoblasts, hepatocytes, and cholangiocytes sorted from embryonic day 10.5 (E10.5) to E17.5 mouse embryos, we found that hepatoblast‐to‐hepatocyte differentiation occurred gradually and followed a linear default pathway. As more cells became fully differentiated hepatocytes, the number of proliferating cells decreased.
Role of ErbB/HER family of receptor tyrosine kinases in cholangiocyte biology
Anna Pellat, Javier Vaquero, Laura Fouassier – 3 July 2017 – The ErbB/HER family comprises four distinct tyrosine kinase receptors, EGFR/ErbB1/HER1, ErbB2/HER2, ErbB3/HER3, and ErbB4/HER4, which trigger intracellular signals at the origin of essential cellular functions, including differentiation, proliferation, survival, and migration. Epithelial cells, named cholangiocytes, that line intrahepatic and extrahepatic bile ducts, contribute substantially to biliary secretory functions and bile transport.