Lean NAFLD: A not so benign condition?
Lisa B. VanWagner, Matthew J. Armstrong – 16 January 2018
A new mechanism of action of glucagon‐like peptide‐1 agonist in hepatic steatosis: Promotion of hepatic insulin clearance through induction of carcinoembryonic antigen‐related cell adhesion molecule 1
Torrey Y. Czech, Qinglan Wang, Ekihiro Seki – 16 January 2018
Cellular Membrane Trafficking Machineries Used by the Hepatitis Viruses
Jun Inoue, Masashi Ninomiya, Tooru Shimosegawa, Mark A. McNiven – 13 January 2018 – While the life cycles of hepatitis viruses (A, B, C, D, and E) have been modestly characterized, recent intensive studies have provided new insights. Because these viruses “hijack” the membrane trafficking of the host cell machinery during replicative propagation, it is essential to determine and understand these specific cellular pathways. Hepatitis B virus (HBV) and hepatitis C virus are well known as leading causes of liver cirrhosis and hepatocellular carcinoma.
Cellular Membrane Trafficking Machineries Used by the Hepatitis Viruses
Jun Inoue, Masashi Ninomiya, Tooru Shimosegawa, Mark A. McNiven – 13 January 2018 – While the life cycles of hepatitis viruses (A, B, C, D, and E) have been modestly characterized, recent intensive studies have provided new insights. Because these viruses “hijack” the membrane trafficking of the host cell machinery during replicative propagation, it is essential to determine and understand these specific cellular pathways. Hepatitis B virus (HBV) and hepatitis C virus are well known as leading causes of liver cirrhosis and hepatocellular carcinoma.
Hepatic PPARα function is controlled by polyubiquitination and proteasome‐mediated degradation through the coordinated actions of PAQR3 and HUWE1
Zilong Zhao, Daqian Xu, Zheng Wang, Lin Wang, Ruomei Han, Zhenzhen Wang, Lujian Liao, Yan Chen – 13 January 2018 – Peroxisome proliferator‐activated receptor α (PPARα) is a key transcriptional factor that regulates hepatic lipid catabolism by stimulating fatty acid oxidation and ketogenesis in an adaptive response to nutrient starvation. However, how PPARα is regulated by posttranslational modification is poorly understood.
Primary biliary cholangitis, DNA, and beyond: The Relative contribution of genes
Aliya F. Gulamhusein, Konstantinos N. Lazaridis – 13 January 2018
A fixed partial epithelial‐mesenchymal transition (EMT) triggers carcinogenesis, whereas asymmetrical division of hybrid EMT cells drives cancer progression
Evgeny V. Denisov, Vladimir M. Perelmuter – 13 January 2018
Identification of theranostic biomarkers to improve the stratification of patients with pediatric liver cancer: Opportunities and challenges
Carolina Armengol, Stefano Cairo – 12 January 2018
MAIT cells are chronically activated in patients with autoimmune liver disease and promote profibrogenic hepatic stellate cell activation
Katrin Böttcher, Krista Rombouts, Francesca Saffioti, Davide Roccarina, Matteo Rosselli, Andrew Hall, TuVinh Luong, Emmanuel A. Tsochatzis, Douglas Thorburn, Massimo Pinzani – 12 January 2018 – Autoimmune liver diseases (AILDs) are chronic liver pathologies characterized by fibrosis and cirrhosis due to immune‐mediated liver damage.
Serologic responses and effectiveness of hepatitis A vaccination among human immunodeficiency virus–positive individuals during the outbreak of acute hepatitis A
Kuan‐Yin Lin, Szu‐Min Hsieh, Hsin‐Yun Sun, Yi‐Chun Lo, Wang‐Huei Sheng, Yu‐Chung Chuang, Aristine Cheng, Sung‐Ching Pan, Guan‐Jhou Chen, Chien‐Ching Hung, Shan‐Chwen Chang – 12 January 2018 – Outbreaks of hepatitis A virus (HAV) infection have been occurring among men who have sex with men in the Asia‐Pacific region, the United States, and several European countries since June 2015 and recently among persons who are homeless and use illicit drugs in the United States.