Hemostatic Alterations in Patients With Cirrhosis: From Primary Hemostasis to Fibrinolysis

Maxime G. Zermatten, Montserrat Fraga, Darius Moradpour, Debora Bertaggia Calderara, Alessandro Aliotta, Guido Stirnimann, Andrea De Gottardi, Lorenzo Alberio – 23 February 2020 – In the setting of liver cirrhosis (LC), profound hemostatic changes occur, which affect primary hemostasis, coagulation, and fibrinolysis. They involve prohemorrhagic and prothrombotic alterations at each of these steps. Patients with cirrhosis exhibit multifactorial thrombocytopenia and in vitro thrombocytopathy, counterbalanced by increased von Willebrand factor.

Hemostatic Alterations in Patients With Cirrhosis: From Primary Hemostasis to Fibrinolysis

Maxime G. Zermatten, Montserrat Fraga, Darius Moradpour, Debora Bertaggia Calderara, Alessandro Aliotta, Guido Stirnimann, Andrea De Gottardi, Lorenzo Alberio – 23 February 2020 – In the setting of liver cirrhosis (LC), profound hemostatic changes occur, which affect primary hemostasis, coagulation, and fibrinolysis. They involve prohemorrhagic and prothrombotic alterations at each of these steps. Patients with cirrhosis exhibit multifactorial thrombocytopenia and in vitro thrombocytopathy, counterbalanced by increased von Willebrand factor.

Inflammation‐Induced Long Intergenic Noncoding RNA (LINC00665) Increases Malignancy Through Activating the Double‐Stranded RNA–Activated Protein Kinase/Nuclear Factor Kappa B Pathway in Hepatocellular Carcinoma

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