Validation of a Simple Quality‐of‐Life Score for Identification of Minimal and Prediction of Overt Hepatic Encephalopathy

Mette Munk Lauridsen, Peter Jepsen, Charlotte Wilhelmina Wernberg, Ove B. Schaffalitzky de Muckadell, Jasmohan S. Bajaj, Hendrik Vilstrup – 3 July 2020 – Minimal hepatic encephalopathy (MHE) is underdiagnosed because most clinics refrain from psychometric testing. Diagnostic activities need to go up so patients with MHE can get the treatment their condition requires. The sickness impact profile questionnaire for covert hepatic encephalopathy (SIPCHE) score is based on quality‐of‐life outcomes and has been proposed as a simple, patient‐administered diagnostic score for grade 1 and MHE.

Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH

Davide Povero, Hirokazu Yamashita, Wenhua Ren, Mani G. Subramanian, Robert P. Myers, Akiko Eguchi, Douglas A. Simonetto, Zachary D. Goodman, Stephen A. Harrison, Arun J. Sanyal, Jaime Bosch, Ariel E. Feldstein – 3 July 2020 – Nonalcoholic fatty liver disease (NAFLD) is currently one of most common forms of chronic liver disease globally.

MicroRNAs 155‐5p, 122‐5p, and 181a‐5p Identify Patients With Graft Dysfunction Due to T Cell–Mediated Rejection After Liver Transplantation

Pablo Ruiz, Olga Millán, Jose Ríos, Alba Díaz, Lydia Sastre, Jordi Colmenero, Gonzalo Crespo, Mercè Brunet, Miquel Navasa – 2 July 2020 – MicroRNAs (miRNAs) are small noncoding RNAs that can be detected in plasma and whose expression is associated with pathological processes. The role of miRNAs in the noninvasive diagnosis of T cell–mediated rejection (TCMR) after liver transplantation (LT) is unclear.

REPLY:

Fang Lei, Ye‐Mao Liu, Feng Zhou, Juan‐Juan Qin, Xiaodong Huang, Bing‐Hong Zhang, Hongliang Li, Yufeng Yuan – 2 July 2020

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