Metabolic Profiling of Bile Acids in the Urine of Patients with Alcohol‐Associated Liver Disease
Liqing He, Vatsalya Vatsalya, Xipeng Ma, Jiayang Zhang, Xinmin Yin, Seongho Kim, Wenke Feng, Craig J. McClain, Xiang Zhang – 19 January 2021 – Bile acids (BAs) play important functions in the development of alcohol‐associated liver disease (ALD). In the current study, urine BA concentrations in 38 patients with well‐described alcohol‐associated hepatitis (AH) as characterized by Model for End‐Stage Liver Disease (MELD), 8 patients with alcohol‐use disorder (AUD), and 19 healthy controls (HCs) were analyzed using liquid chromatography–mass spectrometry.