Liver Transplantation for Langerhans Cell Histiocytosis: A US Population‐Based Analysis and Systematic Review of the Literature

Ioannis A. Ziogas, Christos D. Kakos, W. Kelly Wu, Martin I. Montenovo, Lea K. Matsuoka, Sara Zarnegar‐Lumley, Sophoclis P. Alexopoulos – 22 January 2021 – Langerhans cell histiocytosis (LCH) is the most common histiocytic disorder. Liver involvement is seen in 10.1% to 19.8% of patients with LCH and can lead to secondary sclerosing cholangitis requiring liver transplantation (LT). We describe the characteristics and outcomes of patients undergoing LT for LCH.

LiverLearning®: 2021 Webinar: To Stop or Not to Stop: The Practice of Finite Nucleos(t)ide Analog Therapy

This one-hour webinar will summarize the data that supports the finite strategy of nucleos(t)ide analog (NA) therapy in patients with chronic hepatitis B. Further discussion on how the presenter practices the strategy. In the second half of the webinar, the presenter will present data that argues against the rationale of a finite NA therapy. The presenter will elaborate on why stopping NA before loss of HBsAg cannot be recommended.

Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo‐Independent Regulation of Heat Shock Protein 70 Family Members

Mairene Coto‐Llerena, Nadia Tosti, Stephanie Taha‐Mehlitz, Venkatesh Kancherla, Viola Paradiso, John Gallon, Gaia Bianco, Andrea Garofoli, Souvik Ghosh, Fengyuan Tang, Caner Ercan, Gerhard M. Christofori, Matthias S. Matter, Raoul A. Droeser, Mihaela Zavolan, Savas D. Soysal, Markus Flüe, Otto Kollmar, Luigi M. Terracciano, Charlotte K. Y.

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