Chronic Fatigue Persists in a Significant Proportion of Female Patients After Transplantation for Primary Sclerosing Cholangitis

Ewa Wunsch, Anna Stadnik, Beata Kruk, Benedykt Szczepankiewicz, Katarzyna Kotarska, Marcin Krawczyk, Barbara Górnicka, Maciej Wójcicki, Piotr Milkiewicz – 27 February 2021 – Chronic fatigue and an impairment of general health‐related quality of life (HRQoL) are frequently reported by patients with primary sclerosing cholangitis (PSC). Studies on patients with primary biliary cholangitis (PBC) suggest that, unlike pruritus, fatigue may not be ameliorated by liver transplantation (LT). However, there are few data regarding the assessment of fatigue before and after transplantation in PSC.

Hepatic Steatosis and Ectopic Fat Are Associated With Differences in Subcutaneous Adipose Tissue Gene Expression in People With HIV

Curtis L. Gabriel, Fei Ye, Run Fan, Sangeeta Nair, James G. Terry, John Jeffrey Carr, Heidi Silver, Paxton Baker, LaToya Hannah, Celestine Wanjalla, Mona Mashayekhi, Sam Bailin, Morgan Lima, Beverly Woodward, Manhal Izzy, Jane F. Ferguson, John R. Koethe – 26 February 2021 – Persons with human immunodeficiency virus (PWH) have subcutaneous adipose tissue (SAT) dysfunction related to antiretroviral therapy and direct viral effects, which may contribute to a higher risk of nonalcoholic fatty liver disease compared with human immunodeficiency virus–negative individuals.

Cancer‐Associated Fibroblasts: Orchestrating the Crosstalk Between Liver Cancer Cells and Neutrophils Through the Cardiotrophin‐Like Cytokine Factor 1–Mediated Chemokine (C‐X‐C motif) Ligand 6/TGF‐β Axis

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