Clinical Staging of Mass‐Forming Intrahepatic Cholangiocarcinoma: Computed Tomography Versus Magnetic Resonance Imaging

Yeun‐Yoon Kim, Suk‐Keu Yeom, Hyejung Shin, Sang Hyun Choi, Hyungjin Rhee, Ji Hoon Park, Eun‐Suk Cho, Sumi Park, Seung Soo Lee, Mi‐Suk Park – 23 August 2021 – We compared the performance of computed tomography (CT) and magnetic resonance imaging (MRI) for preoperative clinical staging of mass‐forming intrahepatic cholangiocarcinoma (iCCA), using the eighth American Joint Committee on Cancer (AJCC) system.

RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes

Hyeon‐Ji Kim, Yong‐Hyun Han, Ju‐Yeon Kim, Mi‐Ock Lee – 23 August 2021 – Lysosomes are intracellular acidic organelles with catabolic functions that contribute to the activation of autophagy. Although autophagy abnormality is associated with defects in lysosomal acidification during the progression of nonalcoholic fatty liver disease (NAFLD), the mechanisms of control of lysosomal acidification are not well understood at the molecular level.

Globo H Is a Promising Theranostic Marker for Intrahepatic Cholangiocarcinoma

Tsai‐Hsien Hung, Jung‐Tung Hung, Chiao‐En Wu, Yenlin Huang, Chien‐Wei Lee, Chau‐Ting Yeh, Yi‐Hsiu Chung, Fei‐Yun Lo, Li‐Chun Lai, John K. Tung, John Yu, Chun‐Nan Yeh, Alice L. Yu – 23 August 2021 – Recent studies support the development of cancer therapeutics to target Globo H‐ceramide, the most prevalent tumor‐associated carbohydrate antigen in epithelial cancers.

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