Cholesterol nucleation‐influencing activity in t‐tube bile

Albert K. Groen, Jan P. J. Stout, Jan A. G. Drapers, Frans J. Hoek, Rob Grijm, Guido N. J. Tytgat – 1 March 1988 – Nucleation‐influencing activity was determined in T‐tube bile samples derived from patients with obstructive jaundice. Since native T‐tube bile samples do not nucleate, nucleation‐influencing activity was determined by measuring the influence of T‐tube bile on the nucleation time of model bile.

An experimental transmission of woodchuck hepatitis virus to young chinese marmots

Jin Zhihong, Zhao Guolong, Xiong Shisong, Kou Pingyuan, Ma Lili, Chen Hongtao, Qi Jianying, Ba Qiuju, Mai Kai – 1 March 1988 – Fourteen young Chinese marmots (Marmota bobak sibirica Radde) were randomly allocated to two groups of seven each. They were injected intrahepatically with a standard woodchuck hepatitis virus challenge pool or a negative pool, prepared from sera of woodchucks with and without woodchuck hepatitis virus infection, respectively. Marmot No.

Cytochrome p‐450 gene expression in the functional units of the fetal liver

Jose Chianale, Caroline Dvorak, Donna L. Farmer, Linda Michaels, Jorge J. Gumucio – 1 March 1988 – Hepatocytes of the right and left lobes of the fetal liver are surrounded by different microenvironments. The right and left lobes of the fetal liver are perfused by vascular systems carrying different concentrations of oxygen and constitute distinct functional units. The aim of this study was to assess the expression of the phenobarbital‐inducible cytochrome P‐450 b,e genes in hepatocytes of the right and left fetal liver lobes in mice.

Intraoperative ultrasound in detecting hepatic metastases

Kenneth J. W. Taylor – 1 March 1988 – As a new screening procedure, intraoperative ultrasonography using high‐resolution real‐time instruments was used routinely in 84 colorectal cancer operations to scan the entire liver for liver metastases. In 10 operations (11.9%), intraoperative ultrasonography identified 14 previously unrecognized metastatic tumors, all of which were less than 2 cm in size and were nonpalpable.

Interactions between isolated hepatocytes and kupffer cells in iron metabolism: A possible role for ferritin as an iron carrier protein

Jean‐Claude Sibille, Hitoshi Kondo, Philip Aisen – 1 March 1988 – Like the rat peritoneal macrophage, the isolated Kupffer cell is capable of processing and releasing iron acquired by phagocytosis of immunosensitized homologous red blood cells. When erythrophagocytosis is restrained to levels which do not affect cell viability, about one red cell per macrophage, close to 50% of iron acquired from red cells is released within 24 hr in the form of ferritin.

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